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The pros and cons of gastric bypass surgery – The role of the Roux-limb

The prevalence of overweight and obesity has exploded in the post-industrial era. Life style interventions like dieting and exercise can induce a marked weight loss, but the main problem for most patients is to maintain the reduced body weight over time. Gastric bypass surgery is a commonly performe...

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Bibliographic Details
Published in:Baillière's best practice & research. Clinical gastroenterology 2019-06, Vol.40-41, p.101638-101638, Article 101638
Main Authors: Björklund, Per, Fändriks, Lars
Format: Article
Language:English
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Summary:The prevalence of overweight and obesity has exploded in the post-industrial era. Life style interventions like dieting and exercise can induce a marked weight loss, but the main problem for most patients is to maintain the reduced body weight over time. Gastric bypass surgery is a commonly performed and very effective method for achieving a pronounced and sustained weight loss including metabolic improvements in obese patients. Despite the therapeutic successfulness there are known side-effects like chronic postprandial nausea and pain that in some patients become intractable. The pathophysiology is complex and partly unexplored. The physician or surgeon handling a patient with “post-bariatric symptoms” must be aware of the risk for symptom aggravations due to iatrogenic opioid-associated intestinal dysmotility. The present paper gives a brief overview of obesity surgery and its associated postsurgical conditions with a focus on the unexplored role of the Roux-limb following gastric bypass surgery.
ISSN:1521-6918
1532-1916
DOI:10.1016/j.bpg.2019.101638