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Is it time to rethink standard dosage of exposure-based cognitive behavioral therapy for pediatric obsessive-compulsive disorder?
•This study examined baseline characteristics of children and adolescents with OCD experiencing early treatment response.•A high number of participants evidenced early treatment response, and a clear majority maintained their treatment gains. Younger children were more likely to respond early also w...
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Published in: | Psychiatry research 2019-11, Vol.281, p.112600-112600, Article 112600 |
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creator | Torp, Nor Christian Weidle, Bernhard Thomsen, Per Hove Skarphedinsson, Gudmundur Aalberg, Marianne Nissen, Judith Becker Melin, Karin Holmgren Dahl, Kitty Valderhaug, Robert Ivarsson, Tord |
description | •This study examined baseline characteristics of children and adolescents with OCD experiencing early treatment response.•A high number of participants evidenced early treatment response, and a clear majority maintained their treatment gains. Younger children were more likely to respond early also when effects of age, duration of OCD, and their interaction were considered.•Standard CBT treatment programs should include an evaluation of response to treatment, after seven sessions, with an anticipation that a substantial number of patients, and especially the younger children with less severe OCD will respond early and can be referred to follow up programs.•Treatment planning in the future, should include stepped care models, starting with an initial brief intervention followed by an assessment to determine who is in need of further treatment.
Identifying factors associated with early treatment response is important, because it can help allocate limited resources in psychiatric care more appropriately. This study examined baseline characteristics of participants with early response to exposure-based cognitive behavior therapy (CBT) for pediatric obsessive-compulsive disorder (OCD).
269 participants with OCD, aged 7–17 years, were enrolled in a 14-weeks CBT program. We identified participants with early response to treatment, (CY-BOCS total score of ≤15), by the seventh session.
At week 7, 248 (92.2%) participants were assessed, 38.3% (95% CI 32.4–44.5%, n = 95) were identified as treatment responders. Univariate analyses showed that six baseline characteristics were significantly associated with early treatment response: young age, lower levels of symptom severity, functional impairment, internalizing- and externalizing problems, depressive symptoms, and family accommodation.
These results suggested that treatment plans for younger children with moderate OCD symptoms and no major comorbid disorder should include briefer and less resource demanding treatment formats than the commonly recommended and applied standard doses of 15 CBT sessions. |
doi_str_mv | 10.1016/j.psychres.2019.112600 |
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Identifying factors associated with early treatment response is important, because it can help allocate limited resources in psychiatric care more appropriately. This study examined baseline characteristics of participants with early response to exposure-based cognitive behavior therapy (CBT) for pediatric obsessive-compulsive disorder (OCD).
269 participants with OCD, aged 7–17 years, were enrolled in a 14-weeks CBT program. We identified participants with early response to treatment, (CY-BOCS total score of ≤15), by the seventh session.
At week 7, 248 (92.2%) participants were assessed, 38.3% (95% CI 32.4–44.5%, n = 95) were identified as treatment responders. Univariate analyses showed that six baseline characteristics were significantly associated with early treatment response: young age, lower levels of symptom severity, functional impairment, internalizing- and externalizing problems, depressive symptoms, and family accommodation.
These results suggested that treatment plans for younger children with moderate OCD symptoms and no major comorbid disorder should include briefer and less resource demanding treatment formats than the commonly recommended and applied standard doses of 15 CBT sessions.</description><identifier>ISSN: 0165-1781</identifier><identifier>ISSN: 1872-7123</identifier><identifier>EISSN: 1872-7123</identifier><identifier>DOI: 10.1016/j.psychres.2019.112600</identifier><identifier>PMID: 31622874</identifier><language>eng</language><publisher>Ireland: Elsevier B.V</publisher><subject>Adolescent ; adolescents ; age-children-present ; cbt ; Characteristics of early ; Characteristics of early responds ; Child ; childhood ocd ; Cognitive Behavioral Therapy - methods ; Cognitive Behavioral Therapy - trends ; Cognitive-behavior therapy ; Combined Modality Therapy - methods ; Combined Modality Therapy - trends ; depression ; family accommodation ; Female ; functional impairment ; Health Resources - trends ; Humans ; Male ; moderators ; Obsessive-Compulsive Disorder - diagnosis ; Obsessive-Compulsive Disorder - psychology ; Obsessive-Compulsive Disorder - therapy ; Pediatric OCD ; predictors ; Prospective Studies ; Psychiatry ; Psykiatri ; responds ; Retrospective Studies ; scale ; Treatment Outcome</subject><ispartof>Psychiatry research, 2019-11, Vol.281, p.112600-112600, Article 112600</ispartof><rights>2019 Elsevier B.V.</rights><rights>Copyright © 2019 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-db61dc87de545ca88d3a759456e3fa13154bbb387dbfeb6187cd0b170966879c3</citedby><cites>FETCH-LOGICAL-c444t-db61dc87de545ca88d3a759456e3fa13154bbb387dbfeb6187cd0b170966879c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31622874$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://gup.ub.gu.se/publication/287930$$DView record from Swedish Publication Index$$Hfree_for_read</backlink><backlink>$$Uhttps://gup.ub.gu.se/publication/344137$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Torp, Nor Christian</creatorcontrib><creatorcontrib>Weidle, Bernhard</creatorcontrib><creatorcontrib>Thomsen, Per Hove</creatorcontrib><creatorcontrib>Skarphedinsson, Gudmundur</creatorcontrib><creatorcontrib>Aalberg, Marianne</creatorcontrib><creatorcontrib>Nissen, Judith Becker</creatorcontrib><creatorcontrib>Melin, Karin Holmgren</creatorcontrib><creatorcontrib>Dahl, Kitty</creatorcontrib><creatorcontrib>Valderhaug, Robert</creatorcontrib><creatorcontrib>Ivarsson, Tord</creatorcontrib><title>Is it time to rethink standard dosage of exposure-based cognitive behavioral therapy for pediatric obsessive-compulsive disorder?</title><title>Psychiatry research</title><addtitle>Psychiatry Res</addtitle><description>•This study examined baseline characteristics of children and adolescents with OCD experiencing early treatment response.•A high number of participants evidenced early treatment response, and a clear majority maintained their treatment gains. Younger children were more likely to respond early also when effects of age, duration of OCD, and their interaction were considered.•Standard CBT treatment programs should include an evaluation of response to treatment, after seven sessions, with an anticipation that a substantial number of patients, and especially the younger children with less severe OCD will respond early and can be referred to follow up programs.•Treatment planning in the future, should include stepped care models, starting with an initial brief intervention followed by an assessment to determine who is in need of further treatment.
Identifying factors associated with early treatment response is important, because it can help allocate limited resources in psychiatric care more appropriately. This study examined baseline characteristics of participants with early response to exposure-based cognitive behavior therapy (CBT) for pediatric obsessive-compulsive disorder (OCD).
269 participants with OCD, aged 7–17 years, were enrolled in a 14-weeks CBT program. We identified participants with early response to treatment, (CY-BOCS total score of ≤15), by the seventh session.
At week 7, 248 (92.2%) participants were assessed, 38.3% (95% CI 32.4–44.5%, n = 95) were identified as treatment responders. Univariate analyses showed that six baseline characteristics were significantly associated with early treatment response: young age, lower levels of symptom severity, functional impairment, internalizing- and externalizing problems, depressive symptoms, and family accommodation.
These results suggested that treatment plans for younger children with moderate OCD symptoms and no major comorbid disorder should include briefer and less resource demanding treatment formats than the commonly recommended and applied standard doses of 15 CBT sessions.</description><subject>Adolescent</subject><subject>adolescents</subject><subject>age-children-present</subject><subject>cbt</subject><subject>Characteristics of early</subject><subject>Characteristics of early responds</subject><subject>Child</subject><subject>childhood ocd</subject><subject>Cognitive Behavioral Therapy - methods</subject><subject>Cognitive Behavioral Therapy - trends</subject><subject>Cognitive-behavior therapy</subject><subject>Combined Modality Therapy - methods</subject><subject>Combined Modality Therapy - trends</subject><subject>depression</subject><subject>family accommodation</subject><subject>Female</subject><subject>functional impairment</subject><subject>Health Resources - trends</subject><subject>Humans</subject><subject>Male</subject><subject>moderators</subject><subject>Obsessive-Compulsive Disorder - diagnosis</subject><subject>Obsessive-Compulsive Disorder - psychology</subject><subject>Obsessive-Compulsive Disorder - therapy</subject><subject>Pediatric OCD</subject><subject>predictors</subject><subject>Prospective Studies</subject><subject>Psychiatry</subject><subject>Psykiatri</subject><subject>responds</subject><subject>Retrospective Studies</subject><subject>scale</subject><subject>Treatment Outcome</subject><issn>0165-1781</issn><issn>1872-7123</issn><issn>1872-7123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNqN0U1v1DAQBuAIgehS-AuVj1yy2HFiJydAFZRKlbjA2fLHZNdLEgePs2WP_PN6lbZXOHlkPTMjzVsUV4xuGWXiw2E748nuI-C2oqzbMlYJSl8UG9bKqpSs4i-LTYZNyWTLLoo3iAdKacW67nVxwZmoqlbWm-LvLRKfSPIjkBRIhLT30y-CSU9OR0dcQL0DEnoCf-aAS4TSaARHbNhNPvkjEAN7ffQh6oGkPUQ9n0gfIpnBeZ2ityQYBMRMSxvGeRnOJXEeQ3QQP74tXvV6QHj3-F4WP79--XH9rbz7fnN7_fmutHVdp9IZwZxtpYOmbqxuW8e1bLq6EcB7zThramMMz8D0kG0rraOGSdoJ0crO8suiXOfiPcyLUXP0o44nFbRXu2VW-Wu3KATF65px-f8-H7LjNPv3q59j-L0AJjV6tDAMeoKwoKo4lYxTIZpMxUptDIgR-ufhjKpzvOqgnuJV53jVGm9uvHrcsZgR3HPbU54ZfFoB5EsePUSF1sNkcxYRbFIu-H_teAAgtL4m</recordid><startdate>20191101</startdate><enddate>20191101</enddate><creator>Torp, Nor Christian</creator><creator>Weidle, Bernhard</creator><creator>Thomsen, Per Hove</creator><creator>Skarphedinsson, Gudmundur</creator><creator>Aalberg, Marianne</creator><creator>Nissen, Judith Becker</creator><creator>Melin, Karin Holmgren</creator><creator>Dahl, Kitty</creator><creator>Valderhaug, Robert</creator><creator>Ivarsson, Tord</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>F1U</scope></search><sort><creationdate>20191101</creationdate><title>Is it time to rethink standard dosage of exposure-based cognitive behavioral therapy for pediatric obsessive-compulsive disorder?</title><author>Torp, Nor Christian ; Weidle, Bernhard ; Thomsen, Per Hove ; Skarphedinsson, Gudmundur ; Aalberg, Marianne ; Nissen, Judith Becker ; Melin, Karin Holmgren ; Dahl, Kitty ; Valderhaug, Robert ; Ivarsson, Tord</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-db61dc87de545ca88d3a759456e3fa13154bbb387dbfeb6187cd0b170966879c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adolescent</topic><topic>adolescents</topic><topic>age-children-present</topic><topic>cbt</topic><topic>Characteristics of early</topic><topic>Characteristics of early responds</topic><topic>Child</topic><topic>childhood ocd</topic><topic>Cognitive Behavioral Therapy - methods</topic><topic>Cognitive Behavioral Therapy - trends</topic><topic>Cognitive-behavior therapy</topic><topic>Combined Modality Therapy - methods</topic><topic>Combined Modality Therapy - trends</topic><topic>depression</topic><topic>family accommodation</topic><topic>Female</topic><topic>functional impairment</topic><topic>Health Resources - trends</topic><topic>Humans</topic><topic>Male</topic><topic>moderators</topic><topic>Obsessive-Compulsive Disorder - diagnosis</topic><topic>Obsessive-Compulsive Disorder - psychology</topic><topic>Obsessive-Compulsive Disorder - therapy</topic><topic>Pediatric OCD</topic><topic>predictors</topic><topic>Prospective Studies</topic><topic>Psychiatry</topic><topic>Psykiatri</topic><topic>responds</topic><topic>Retrospective Studies</topic><topic>scale</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Torp, Nor Christian</creatorcontrib><creatorcontrib>Weidle, Bernhard</creatorcontrib><creatorcontrib>Thomsen, Per Hove</creatorcontrib><creatorcontrib>Skarphedinsson, Gudmundur</creatorcontrib><creatorcontrib>Aalberg, Marianne</creatorcontrib><creatorcontrib>Nissen, Judith Becker</creatorcontrib><creatorcontrib>Melin, Karin Holmgren</creatorcontrib><creatorcontrib>Dahl, Kitty</creatorcontrib><creatorcontrib>Valderhaug, Robert</creatorcontrib><creatorcontrib>Ivarsson, Tord</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Göteborgs universitet</collection><jtitle>Psychiatry research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Torp, Nor Christian</au><au>Weidle, Bernhard</au><au>Thomsen, Per Hove</au><au>Skarphedinsson, Gudmundur</au><au>Aalberg, Marianne</au><au>Nissen, Judith Becker</au><au>Melin, Karin Holmgren</au><au>Dahl, Kitty</au><au>Valderhaug, Robert</au><au>Ivarsson, Tord</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is it time to rethink standard dosage of exposure-based cognitive behavioral therapy for pediatric obsessive-compulsive disorder?</atitle><jtitle>Psychiatry research</jtitle><addtitle>Psychiatry Res</addtitle><date>2019-11-01</date><risdate>2019</risdate><volume>281</volume><spage>112600</spage><epage>112600</epage><pages>112600-112600</pages><artnum>112600</artnum><issn>0165-1781</issn><issn>1872-7123</issn><eissn>1872-7123</eissn><abstract>•This study examined baseline characteristics of children and adolescents with OCD experiencing early treatment response.•A high number of participants evidenced early treatment response, and a clear majority maintained their treatment gains. Younger children were more likely to respond early also when effects of age, duration of OCD, and their interaction were considered.•Standard CBT treatment programs should include an evaluation of response to treatment, after seven sessions, with an anticipation that a substantial number of patients, and especially the younger children with less severe OCD will respond early and can be referred to follow up programs.•Treatment planning in the future, should include stepped care models, starting with an initial brief intervention followed by an assessment to determine who is in need of further treatment.
Identifying factors associated with early treatment response is important, because it can help allocate limited resources in psychiatric care more appropriately. This study examined baseline characteristics of participants with early response to exposure-based cognitive behavior therapy (CBT) for pediatric obsessive-compulsive disorder (OCD).
269 participants with OCD, aged 7–17 years, were enrolled in a 14-weeks CBT program. We identified participants with early response to treatment, (CY-BOCS total score of ≤15), by the seventh session.
At week 7, 248 (92.2%) participants were assessed, 38.3% (95% CI 32.4–44.5%, n = 95) were identified as treatment responders. Univariate analyses showed that six baseline characteristics were significantly associated with early treatment response: young age, lower levels of symptom severity, functional impairment, internalizing- and externalizing problems, depressive symptoms, and family accommodation.
These results suggested that treatment plans for younger children with moderate OCD symptoms and no major comorbid disorder should include briefer and less resource demanding treatment formats than the commonly recommended and applied standard doses of 15 CBT sessions.</abstract><cop>Ireland</cop><pub>Elsevier B.V</pub><pmid>31622874</pmid><doi>10.1016/j.psychres.2019.112600</doi><tpages>1</tpages></addata></record> |
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subjects | Adolescent adolescents age-children-present cbt Characteristics of early Characteristics of early responds Child childhood ocd Cognitive Behavioral Therapy - methods Cognitive Behavioral Therapy - trends Cognitive-behavior therapy Combined Modality Therapy - methods Combined Modality Therapy - trends depression family accommodation Female functional impairment Health Resources - trends Humans Male moderators Obsessive-Compulsive Disorder - diagnosis Obsessive-Compulsive Disorder - psychology Obsessive-Compulsive Disorder - therapy Pediatric OCD predictors Prospective Studies Psychiatry Psykiatri responds Retrospective Studies scale Treatment Outcome |
title | Is it time to rethink standard dosage of exposure-based cognitive behavioral therapy for pediatric obsessive-compulsive disorder? |
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