Haematological reference values in Spanish adolescents: the AVENA study

Objectives:  To provide reference values for haematological indices in Spanish adolescents according to age and gender. Methods:  A cross sectional study conducted in five Spanish cities was performed. Blood was drawn from a representative sample of 581 adolescents with age ranging from 13 to 17–18....

Full description

Saved in:
Bibliographic Details
Published in:European journal of haematology 2009-12, Vol.83 (6), p.586-594
Main Authors: Romeo, Javier, Wärnberg, Julia, Gómez-Martínez, Sonia, Díaz, Ligia E., Moreno, Luis A., Castillo, Manuel J., Redondo, Carlos, Baraza, Juan C., Sola, Ricardo, Zamora, Salvador, Marcos, Ascensión
Format: Article
Language:English
Subjects:
Adolescent - physiology
adolescents
AVENA study
Blood Cell Count - standards
Cross-Sectional Studies
Erythrocyte Indices
Female
gender
haematology
Hematocrit - standards
Hematologic Tests - standards
Hemoglobins - analysis
Humans
Male
Medicin och hälsovetenskap
Nutritional Status
reference ranges
Reference Values
Sex Characteristics
Spain
Urban Population
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives:  To provide reference values for haematological indices in Spanish adolescents according to age and gender. Methods:  A cross sectional study conducted in five Spanish cities was performed. Blood was drawn from a representative sample of 581 adolescents with age ranging from 13 to 17–18.5 yr. Age‐ and gender‐specific means, standard deviations and percentiles were determined for the following parameters: total red blood cell counts (RBC), haemoglobin concentration (Hb), haematocrit percentage (Hct), mean corpuscular volume (MCV), mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, red cell distribution width and total white blood cell (WBC) counts as well as counts and percentage of neutrophils, lymphocytes, monocytes, eosinophils and basophils; platelet count (PLT), mean platelet volume and plateletcrit percentage. Results:  Younger male subjects presented lower RBC, Hb, Hct and MCV means that their older counterpart. By contrast these differences were not observed in female subjects. As expected, RBC, Hb and Hct mean values in males were found significantly higher than in girls for all studied age groups. No significant differences were observed in WBC by age and gender. PLT values gradually decreased with age, except for females aged 17–18.5 yr. Conclusion:  The present study provides reference data on the distribution of haematological indices of Spanish adolescents. These data can be useful biomarkers of the nutritional status in adolescents.
ISSN:0902-4441
1600-0609
1600-0609
DOI:10.1111/j.1600-0609.2009.01326.x