Hepatitis C prevalence in injecting drug users in Europe, 1990–2007: impact of study recruitment setting

Monitoring injecting drug users' (IDUs) health is challenging because IDUs form a difficult to reach population. We examined the impact of recruitment setting on hepatitis C prevalence. Individual datasets from 12 studies were merged. Predictors of HCV positivity were sought through a multileve...

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Bibliographic Details
Published in:Epidemiology and infection 2013-03, Vol.141 (3), p.563-572
Main Authors: RONDY, M., WIESSING, L., HUTCHINSON, S. J., MATHEÏ, C., MATHIS, F., MRAVCIK, V., NORDEN, L., ROSIŃSKA, M., SCUTELNICIUC, O., SULIGOI, B., VALLEJO, F., VAN VEEN, M., KRETZSCHMAR, M.
Format: Article
Language:English
Subjects:
Adult
AIDS
Antibodies
Biological and medical sciences
Datasets
Diagnostic tests
Drug abuse
Drug addiction
Drug use
Epidemiology
Europe - epidemiology
Female
Fundamental and applied biological sciences. Psychology
Harm reduction
Hepatitis
Hepatitis C
Hepatitis C - epidemiology
Hepatitis C virus
HIV
Human viral diseases
Humans
Infections
Infectious diseases
Injections
Male
Medical research
Medical sciences
Medicin och hälsovetenskap
Microbiology
Needle-Exchange Programs
Original Papers
Pathogens
Patient Selection
Population estimates
Prevalence
Public health
Research Design
Selection Bias
Sensitivity analysis
Seroepidemiologic Studies
Serology
Substance Abuse Treatment Centers
Substance Abuse, Intravenous - epidemiology
Viral diseases
Viral hepatitis
Viral infections
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Summary:Monitoring injecting drug users' (IDUs) health is challenging because IDUs form a difficult to reach population. We examined the impact of recruitment setting on hepatitis C prevalence. Individual datasets from 12 studies were merged. Predictors of HCV positivity were sought through a multilevel analysis using a mixed-effects logistic model, with study identifier as random intercept. HCV prevalence ranged from 21% to 86% across the studies. Overall, HCV prevalence was higher in IDUs recruited in drug treatment centres compared to those recruited in low-threshold settings (74% and 42%, respectively, P 
ISSN:0950-2688
1469-4409
1469-4409
DOI:10.1017/S0950268812000921