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Associations between cognition and serotonin receptor 1B binding in patients with major depressive disorder – a pilot study

Highlights • Verbal fluency improved after Internet-based CBT in patients with MDD. • Significant correlations were found between cognitive ability and 5-HT1BR binding. • Changes in cognitive performance were correlated with changes in 5-HT1BR binding after ICBT treatment.

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Bibliographic Details
Published in:Psychiatry research. Neuroimaging 2017-09, Vol.267, p.15-21
Main Authors: Tangen, Ämma, Borg, Jacqueline, Tiger, Mikael, Varnäs, Katarina, Sorjonen, Kimmo, Lindefors, Nils, Halldin, Christer, Lundberg, Johan
Format: Article
Language:English
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Summary:Highlights • Verbal fluency improved after Internet-based CBT in patients with MDD. • Significant correlations were found between cognitive ability and 5-HT1BR binding. • Changes in cognitive performance were correlated with changes in 5-HT1BR binding after ICBT treatment.
ISSN:0925-4927
1872-7506
1872-7506
DOI:10.1016/j.pscychresns.2017.06.001