Childhood onset inflammatory bowel disease and risk of cancer: a Swedish nationwide cohort study 1964-2014

Objective To assess risk of cancer in patients with childhood onset inflammatory bowel disease in childhood and adulthood.Design Cohort study with matched general population reference individuals using multivariable Cox regression to estimate hazard ratios.Setting Swedish national patient register (...

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Bibliographic Details
Published in:BMJ (Online) 2017-09, Vol.358, p.j3951-j3951
Main Authors: Olén, O, Askling, J, Sachs, MC, Frumento, P, Neovius, M, Smedby, KE, Ekbom, A, Malmborg, P, Ludvigsson, JF
Format: Article
Language:English
Subjects:
Adults
Cancer
Child
Children
Classification
Cohort analysis
Cohort Studies
Colitis, Ulcerative - epidemiology
Colitis, Ulcerative - therapy
Colorectal cancer
Comorbidity
Crohn Disease - epidemiology
Crohn Disease - therapy
Crohn's disease
Female
Gastroenterology
Gastrointestinal cancer
Gastrointestinal Neoplasms - epidemiology
Health risk assessment
Humans
Incidence
Inflammatory bowel disease
Inflammatory bowel diseases
Intestine
Lymphoma
Lymphoma - epidemiology
Male
Medicin och hälsovetenskap
Melanoma
Neoplasms - epidemiology
Patients
Population
Population studies
Risk assessment
Risk Factors
Skin cancer
Skin Neoplasms - epidemiology
Surveillance
Sweden - epidemiology
Ulcerative colitis
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Summary:Objective To assess risk of cancer in patients with childhood onset inflammatory bowel disease in childhood and adulthood.Design Cohort study with matched general population reference individuals using multivariable Cox regression to estimate hazard ratios.Setting Swedish national patient register (both inpatient and non-primary outpatient care) 1964-2014.Participants Incident cases of childhood onset (
ISSN:1756-1833
0959-8138
1756-1833
DOI:10.1136/bmj.j3951