The effect of concomitant hand osteoarthritis on pain and disease activity in patients with rheumatoid arthritis

Introduction Pain is a core complaint among rheumatoid arthritis (RA) patients, and persistent pain requires treatment adjustments according to current strategies. We aimed to quantify the impact of hand osteoarthritis (OA) on health status and residual pain in patients with RA. Methods This cross-s...

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Bibliographic Details
Published in:Clinical rheumatology 2019-10, Vol.38 (10), p.2709-2716
Main Authors: Ruiz-Medrano, Emmanuel, Espinosa-Ortega, Hector Fabricio, Arce-Salinas, Cesar Alejandro
Format: Article
Language:English
Subjects:
Activities of Daily Living
Aged
Arthritis, Rheumatoid - complications
Arthritis, Rheumatoid - physiopathology
Coexistence
Cross-Sectional Studies
Female
Hand
Hand - physiopathology
Health risk assessment
Health Status
Humans
Joint diseases
Male
Medicin och hälsovetenskap
Medicine
Medicine & Public Health
Middle Aged
Original Article
Osteoarthritis
Osteoarthritis - complications
Osteoarthritis - physiopathology
Pain
Pain - physiopathology
Pain Management
Pain Measurement
Patients
Quality of Life
Rheumatoid arthritis
Rheumatology
Self Report
Severity of Illness Index
Surveys and Questionnaires
Visual Analog Scale
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Summary:Introduction Pain is a core complaint among rheumatoid arthritis (RA) patients, and persistent pain requires treatment adjustments according to current strategies. We aimed to quantify the impact of hand osteoarthritis (OA) on health status and residual pain in patients with RA. Methods This cross-sectional survey compared RA patients with and without osteoarthritis of the hand. The main outcome was pain intensity. Other measurements included disease activity scores (the Disease Activity Score 28-joints; the Simplified Disease Activity Index, SDAI; the Clinical Disease Activity Index, CDAI), functional disability and self-reported quality of life, and the proportion of patients with residual pain (Patient Acceptable Symptom State, PASS). Results Eighty-one patients were analyzed, including 39 with RA and OA and 42 with RA only. The patients were mainly women (94%), with a median disease duration of 13 years. This group also reported a higher intensity of pain (visual analogue scale, VAS 70 mm vs. 30 mm; p  = 0.003), higher disease activity (3.89 vs. 2.88; p  = 0.001), and greater functional disability irrespective of treatment and comorbidities. A strong correlation ( r 2  = 0.69; p  
ISSN:0770-3198
1434-9949
1434-9949
DOI:10.1007/s10067-019-04574-6