Levels of ochratoxin A in blood from Norwegian and Swedish blood donors and their possible correlation with food consumption

Blood levels of ochratoxin A were determined in 406 Scandinavian blood donors (206 from Oslo, Norway, and 200 from Visby on the island of Gotland, Sweden), using an HPLC method. In connection with the blood collection, the subjects were asked to fill in a food questionnaire to obtain individual diet...

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Bibliographic Details
Published in:Food and chemical toxicology 2001-12, Vol.39 (12), p.1145-1151
Main Authors: Thuvander, A, Paulsen, J.E, Axberg, K, Johansson, N, Vidnes, A, Enghardt-Barbieri, H, Trygg, K, Lund-Larsen, K, Jahrl, S, Widenfalk, A, Bosnes, V, Alexander, J, Hult, K, Olsen, M
Format: Article
Language:English
Subjects:
Adult
Animals
Beer - analysis
Biological and medical sciences
Biomarker
Blood Donors
Carcinogens - analysis
Chromatography, High Pressure Liquid
Dietary intake
Edible Grain - chemistry
Female
Food Analysis
Food Contamination - analysis
Human exposure
Humans
Male
Meat - analysis
Medical sciences
Medicin och hälsovetenskap
Norway - epidemiology
Ochratoxin A
Ochratoxins - blood
Plant poisons toxicology
plasma
risk assessment
Statistics as Topic
Surveys and Questionnaires
Sweden - epidemiology
Swine
Toxicology
Wine - analysis
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Summary:Blood levels of ochratoxin A were determined in 406 Scandinavian blood donors (206 from Oslo, Norway, and 200 from Visby on the island of Gotland, Sweden), using an HPLC method. In connection with the blood collection, the subjects were asked to fill in a food questionnaire to obtain individual dietary information relevant to ochratoxin A exposure. The mean plasma level of ochratoxin A was 0.18 ng/ml in Oslo and slightly higher, 0.21 ng/ml ( P=0.046) in Visby. There was no correlation between plasma levels of ochratoxin A and the estimated total dietary intake of ochratoxin A based on consumption data and levels in food (retrieved from the literature), neither was the plasma level of ochratoxin A correlated with the total amount of food consumed. However, consumption of several foods, including cereal products, wine, beer and pork, were to some minor degree related to high plasma levels of ochratoxin A. The strongest correlations (correlation coefficient r>0.4; P
ISSN:0278-6915
1873-6351
1873-6351
DOI:10.1016/S0278-6915(01)00080-1