Calpain-Mediated Bid Cleavage and Calpain-Independent Bak Modulation: Two Separate Pathways in Cisplatin-Induced Apoptosis

• Published in: Molecular and Cellular Biology 2002-05, Vol.22 (9), p.3003-3013
• Main Authors: Mandic, Aleksandra, Viktorsson, Kristina, Strandberg, Linda, Heiden, Thomas, Hansson, Johan, Linder, Stig, Shoshan, Maria C.
• Format: Article
• Language: English
• Subjects: Amino Acid Sequence; Apoptosis - drug effects; Arginine - metabolism; Bak protein; bcl-2 Homologous Antagonist-Killer Protein; BH3 Interacting Domain Death Agonist Protein; Bid protein; Calcium - metabolism; calpain; Calpain - antagonists & inhibitors; Calpain - metabolism; calpeptin; Carrier Proteins - chemistry; Carrier Proteins - metabolism; Cathepsin L; Cathepsins - antagonists & inhibitors; Cathepsins - metabolism; Cell Growth and Development; Cisplatin - pharmacology; Cysteine Endopeptidases; Cytochrome c Group - metabolism; Dipeptides - pharmacology; Enzyme Activation; Glycine - metabolism; Humans; Intracellular Membranes - metabolism; Medicin och hälsovetenskap; Membrane Potentials - drug effects; Membrane Proteins - metabolism; Mitochondria - metabolism; Molecular Sequence Data; PD150606; Protein Processing, Post-Translational - drug effects; Signal Transduction; Time Factors; Tumor Cells, Cultured
• ISSN: 0270-7306; 1098-5549; 1098-5549
• DOI: 10.1128/MCB.22.9.3003-3013.2002

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