Modification of serum fatty acids in preterm infants by parenteral lipids and enteral docosahexaenoic acid/arachidonic acid: A secondary analysis of the Mega Donna Mega trial

Preterm infants risk deficits of long-chain polyunsaturated fatty acids (LCPUFAs) that may contribute to morbidities and hamper neurodevelopment. We aimed to determine longitudinal serum fatty acid profiles in preterm infants and how the profiles are affected by enteral and parenteral lipid sources....

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Bibliographic Details
Published in:Clinical nutrition (Edinburgh, Scotland) Scotland), 2023-06, Vol.42 (6), p.962-971
Main Authors: Sjöbom, Ulrika, Andersson, Mats X., Pivodic, Aldina, Lund, Anna-My, Vanpee, Mireille, Hansen-Pupp, Ingrid, Ley, David, Wackernagel, Dirk, Sävman, Karin, Smith, Lois E.H., Löfqvist, Chatarina, Hellström, Ann, Nilsson, Anders K.
Format: Article
Language:English
Subjects:
Arachidonic Acid
Clinical Medicine
Cohort Studies
dha
diet
Docosahexaenoic acid
Docosahexaenoic Acids
Extremely preterm infants
Fatty Acids
Humans
Infant
Infant, Extremely Premature
Infant, Newborn
Intravenous lipid emulsion
Klinisk medicin
LCPUFA
Medical and Health Sciences
Medicin och hälsovetenskap
Nutrition & Dietetics
Parenteral nutrition
Pediatrics
Pediatrik
Phospholipids
plasma
supplementation
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Summary:Preterm infants risk deficits of long-chain polyunsaturated fatty acids (LCPUFAs) that may contribute to morbidities and hamper neurodevelopment. We aimed to determine longitudinal serum fatty acid profiles in preterm infants and how the profiles are affected by enteral and parenteral lipid sources. Cohort study analyzing fatty acid data from the Mega Donna Mega study, a randomized control trial with infants born
ISSN:0261-5614
1532-1983
DOI:10.1016/j.clnu.2023.04.020