Pain in individuals with idiopathic inflammatory myopathies, other systemic autoimmune rheumatic diseases, and without rheumatic diseases: A report from the COVAD study

• Published in: International journal of rheumatic diseases 2023-04, Vol.26 (4), p.727-739
• Main Authors: Shinjo, Samuel Katsuyuki, Kim, Minchul, Hoff, Leonardo Santos, Missé, Rafael Giovani, Sen, Parikshit, Naveen, R., Day, Jessica, Cordeiro, Rafael Alves, Júnior, Jucier Gonçalves, Chatterjee, Tulika, Lilleker, James B., Agarwal, Vishwesh, Kardes, Sinan, Milchert, Marcin, Gheita, Tamer, Salim, Babur, Velikova, Tsvetelina, Gracia‐Ramos, Abraham Edgar, Parodis, Ioannis, O'Callaghan, Albert Selva, Nikiphorou, Elena, Makol, Ashima, Tan, Ai Lyn, Cavagna, Lorenzo, Saavedra, Miguel A., Ziade, Nelly, Knitza, Johannes, Kuwana, Masataka, Nune, Arvind, Distler, Oliver, Chinoy, Hector, Agarwal, Vikas, Aggarwal, Rohit, Gupta, Latika
• Format: Article
• Language: English
• Subjects: Autoantibodies; Autoimmune diseases; Autoimmune Diseases - complications; Autoimmune Diseases - diagnosis; Autoimmune Diseases - epidemiology; COVID-19; COVID-19 - complications; COVID-19 Vaccines; Cross-Sectional Studies; Female; functional status; Gender; Humans; Inflammation; Inflammatory diseases; Medicin och hälsovetenskap; Musculoskeletal diseases; Myositis; Myositis - complications; Myositis - diagnosis; Myositis - epidemiology; Pain; Regression analysis; Rheumatic diseases; Rheumatic Diseases - complications; Rheumatic Diseases - diagnosis; Rheumatic Diseases - epidemiology; Vaccination
• ISSN: 1756-1841; 1756-185X; 1756-185X
• DOI: 10.1111/1756-185X.14636

Objectives To compare pain intensity among individuals with idiopathic inflammatory myopathies (IIMs), other systemic autoimmune rheumatic diseases (AIRDs), and without rheumatic disease (wAIDs). Methods Data were collected from the COVID‐19 Vaccination in Autoimmune Diseases (COVAD) study, an international cross‐sectional online survey, from December 2020 to August 2021. Pain experienced in the preceding week was assessed using numeral rating scale (NRS). We performed a negative binomial regression analysis to assess pain in IIMs subtypes and whether demographics, disease activity, general health status, and physical function had an impact on pain scores. Results Of 6988 participants included, 15.1% had IIMs, 27.9% had other AIRDs, and 57.0% were wAIDs. The median pain NRS in patients with IIMs, other AIRDs, and wAIDs were 2.0 (interquartile range [IQR] = 1.0–5.0), 3.0 (IQR = 1.0–6.0), and 1.0 (IQR = 0–2.0), respectively (P