Prospective Evaluation of Complications and Associated Risk Factors in Breast Cancer Surgery

Background. Surgical site infection (SSI) is a well-known complication after breast cancer surgery. The primary aim was to assess risk factors for SSI. Risk factors for other wound complications were also studied. Materials and Methods. In this prospectively registered cohort study, patients who und...

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Bibliographic Details
Published in:Journal of oncology 2022, Vol.2022, p.6601066-8
Main Authors: Adwall, Linda, Hultin, Hella, Mani, Maria, Norlén, Olov
Format: Article
Language:English
Subjects:
Antibiotics
Biopsy
Body mass index
Breast cancer
Cancer surgery
Chemotherapy
Cohort analysis
Complications and side effects
Diabetes
Disease prevention
Hematoma
Lumpectomy
Lymphatic system
Mammaplasty
Mastectomy
Medical research
Medicin och hälsovetenskap
Medicine, Experimental
Patients
Risk factors
Skin
Surgeons
Wound dehiscence
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Description
Summary:Background. Surgical site infection (SSI) is a well-known complication after breast cancer surgery. The primary aim was to assess risk factors for SSI. Risk factors for other wound complications were also studied. Materials and Methods. In this prospectively registered cohort study, patients who underwent breast-conserving surgery (BCS) or mastectomy between May 2017 and May 2019 were included. Data included patient and treatment characteristics, infection, and wound complication rates. Risk factors for SSI and wound complications were analyzed with simple and multiple logistic regression. Results. The study cohort consisted of 592 patients who underwent 707 procedures. There were 66 (9.3%) SSI and 95 (13.4%) wound complications. “BMI>25,” “oncoplastic BCS,” “reoperation within 24 hour,” and “prolonged operative time” were risk factors for SSI with simple analysis. BMI 25-30 and >30 remained as significant risk factors for SSI with adjusted analysis. Risk factors for “any wound complication” with adjusted analysis were “mastectomy with/without reconstruction” in addition to “BMI 25-30” and “BMI>30.” Conclusion. The only significant risk factor for SSI on multivariable analysis were BMI 25-30 and BMI>30. Significant risk factors for “any wound complication” on multivariable analysis were “mastectomy with/without reconstruction” as well as “BMI 25-30” and “BMI>30.”
ISSN:1687-8450
1687-8469
1687-8450
1687-8469
DOI:10.1155/2022/6601066