Fiber intake and health in people with chronic kidney disease

• Published in: Clinical kidney journal 2022-02, Vol.15 (2), p.213-225
• Main Authors: Su, Guobin, Qin, Xindong, Yang, Changyuan, Sabatino, Alice, Kelly, Jaimon T, Avesani, Carla Maria, Carrero, Juan Jesus
• Format: Article
• Language: English
• Subjects: Chronic kidney failure; CKJ Review; Complications and side effects; Development and progression; Inflammation; Medical research; Medicin och hälsovetenskap; Medicine, Experimental; Microbiota (Symbiotic organisms); Patient compliance; Type 2 diabetes
• ISSN: 2048-8505; 2048-8513
• DOI: 10.1093/ckj/sfab169

Abstract Emerging evidence suggests that diet, particularly one that is rich in dietary fiber, may prevent the progression of chronic kidney disease (CKD) and its associated complications in people with established CKD. This narrative review summarizes the current evidence and discusses the opportunities for increasing fiber intake in people with CKD to improve health and reduce disease complications. A higher consumption of fiber exerts multiple health benefits, such as increasing stool output, promoting the growth of beneficial microbiota, improving the gut barrier and decreasing inflammation, as well decreasing uremic toxin production. Despite this, the majority of people with CKD consume less than the recommended dietary fiber intake, which may be due in part to the competing dietary potassium concern. Based on existing evidence, we see benefits from adopting a higher intake of fiber-rich food, and recommend cooperation with the dietitian to ensure an adequate diet plan. We also identify knowledge gaps for future research and suggest means to improve patient adherence to a high-fiber diet.