Laryngeal disorders in people living with HIV

Several studies have shown that HIV infected individuals are at higher risk compared to the general population of developing non-AIDS defining conditions such as some types of cancer, kidney disease, liver disease and others. In this case-control study, we compared the incidence of laryngeal disorde...

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Bibliographic Details
Published in:American journal of otolaryngology 2022-01, Vol.43 (1), p.103234-103234, Article 103234
Main Authors: Piersiala, Krzysztof, Weinreb, Samuel F., Akst, Lee M., Hillel, Alexander T., Best, Simon R.
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Anti-HIV Agents - therapeutic use
Cancer
Case studies
Case-Control Studies
Control charts
Deglutition Disorders - epidemiology
Deglutition Disorders - virology
Disorders
Female
Fungi
HIV
HIV Infections - complications
HIV Infections - virology
Human immunodeficiency virus
Humans
Incidence
Kidney diseases
Laryngeal cancer
Laryngeal Diseases - epidemiology
Laryngeal Diseases - virology
Laryngeal disorders
Laryngitis
Liver cancer
Liver diseases
Male
Medical records
Medicin och hälsovetenskap
Middle Aged
Papilloma
Pathology
Patients
Prevalence
Respiratory tract
Retrospective Studies
Squamous cell carcinoma
Swallowing
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Summary:Several studies have shown that HIV infected individuals are at higher risk compared to the general population of developing non-AIDS defining conditions such as some types of cancer, kidney disease, liver disease and others. In this case-control study, we compared the incidence of laryngeal disorders between a treatment-seeking HIV-positive population and uninfected controls. We aimed to investigate whether there are any laryngeal disorders that are overrepresented in HIV-positive individuals. This was a case-control study based on retrospective chart review, comparing the incidence of laryngeal, airway, and swallowing disorders in sixty-nine HIV positive individuals and 4178 HIV negative controls treated between January 1, 2016 and December 31, 2017, at the Johns Hopkins Voice Center. A majority of HIV-infected patients (59.4%) had at least one diagnosis belonging to the Vocal cord pathology category compared to 48.2% of controls (OR 1.57, p = 0.065). Compared to the entire treatment-seeking population, HIV patients were more likely to present with laryngeal cancer (15.9% vs. 3.4% in controls, OR 5.43, p 
ISSN:0196-0709
1532-818X
1532-818X
DOI:10.1016/j.amjoto.2021.103234