Health-related quality of life after first-ever acute ischemic stroke: associations with cardiovascular health metrics

Purpose To investigate the associations between cardiovascular health (CVH) metrics and health-related quality of life (HRQL) among patients with ischemic stroke in China, and further explore the role of physical and cognitive function in their associations. Methods This hospital-based study include...

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Bibliographic Details
Published in:Quality of life research 2021-10, Vol.30 (10), p.2907-2917
Main Authors: She, Rui, Yan, Zhongrui, Hao, Yanlei, Zhang, Zuoji, Du, Yifeng, Liang, Yajun, Vetrano, Davide L., Dekker, Joost, Bai, Bo, Lau, Joseph T. F., Qiu, Chengxuan
Format: Article
Language:English
Subjects:
Adult
Blood pressure
Brain Ischemia - epidemiology
Cardiovascular disease risks
Cardiovascular Diseases - epidemiology
Cognitive ability
Cognitive impairment
Exercise
Female
Function
Health Status
Humans
Ischemia
Ischemic Stroke
Male
Medicin och hälsovetenskap
Medicine
Medicine & Public Health
Public Health
Quality Indicators, Health Care
Quality of life
Quality of Life - psychology
Quality of Life Research
Risk Factors
Sociology
Stroke
Stroke - epidemiology
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Summary:Purpose To investigate the associations between cardiovascular health (CVH) metrics and health-related quality of life (HRQL) among patients with ischemic stroke in China, and further explore the role of physical and cognitive function in their associations. Methods This hospital-based study included 1714 patients with first-ever acute ischemic stroke (age ≥ 40 years; 36.7% women) who were admitted to two university hospitals in Shandong, China. We collected information on seven CVH metrics (smoking, body mass index, diet, physical activity, blood pressure, total cholesterol, and fasting blood glucose) through interviews, clinical examinations, and laboratory tests. EQ-5D-3L was used to assess HRQL. Cognitive and physical functioning was assessed by the Montreal Cognitive Assessment test and Barthel index, respectively. Data were analyzed using the general linear regression models. Results The average score (SD) was 0.746 (0.23) for HRQL index and 72.7 (15.8) for self-rated health. Optimal levels of four individual CVH metric components (diet, physical activity, blood pressure, and blood glucose) and a higher composite CVH score were significantly associated with a greater HRQL index and better self-rated health ( p  
ISSN:0962-9343
1573-2649
1573-2649
DOI:10.1007/s11136-021-02853-x