Pre‐oxygenation using high‐flow nasal oxygen vs. tight facemask during rapid sequence induction

Summary Pre‐oxygenation using high‐flow nasal oxygen can decrease the risk of desaturation during rapid sequence induction in patients undergoing emergency surgery. Previous studies were single‐centre and often in limited settings. This randomised, international, multicentre trial compared high‐flow...

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Bibliographic Details
Published in:Anaesthesia 2021-09, Vol.76 (9), p.1176-1183
Main Authors: Sjöblom, A., Broms, J., Hedberg, M., Lodenius, Å., Furubacke, A., Henningsson, R., Wiklund, A., Nabecker, S., Theiler, L., Jonsson Fagerlund, M.
Format: Article
Language:English
Subjects:
Carbon dioxide
Desaturation
Emergencies
emergency
Emergency medical care
Intubation
Medicin och hälsovetenskap
Oxygen
oxygen desaturation
Oxygenation
Patients
pre‐oxygenation
rapid sequence induction
Regurgitation
Surgery
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Summary:Summary Pre‐oxygenation using high‐flow nasal oxygen can decrease the risk of desaturation during rapid sequence induction in patients undergoing emergency surgery. Previous studies were single‐centre and often in limited settings. This randomised, international, multicentre trial compared high‐flow nasal oxygen with standard facemask pre‐oxygenation for rapid sequence induction in emergency surgery at all hours of the day and night. A total of 350 adult patients from six centres in Sweden and one in Switzerland undergoing emergency surgery where rapid sequence induction was required were included and randomly allocated to pre‐oxygenation with 100% oxygen using high‐flow nasal oxygen or a standard tight‐fitting facemask. The primary outcome was the number of patients developing oxygen saturations
ISSN:0003-2409
1365-2044
1365-2044
DOI:10.1111/anae.15426