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Platelets mediate serological memory to neutralize viruses in vitro and in vivo

•Platelets contain virus-specific IgGs that potently diminish viral infection in vitro and in vivo.•Release of platelet IgG is more efficient at virus neutralization than equal amounts of plasma IgG. [Display omitted]

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Published in:Blood advances 2020-08, Vol.4 (16), p.3971-3976
Main Authors: Schrottmaier, Waltraud C., Salzmann, Manuel, Badrnya, Sigrun, Mussbacher, Marion, Kral-Pointner, Julia B., Morava, Susanne, Pirabe, Anita, Brunnthaler, Laura, Yaiw, Koon C., Heber, Ulrike M., Pereyra, David, Andersen, Jan T., Bergthaler, Andreas, Söderberg-Nauclér, Cecilia, Karlsson, Mikael C.I., Assinger, Alice, Forsell, Mattias N.E.
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cited_by cdi_FETCH-LOGICAL-c629t-2578e83c52b6bc3434b99b9b6c023b7a9f560266739b19ba406250a6d221891a3
cites cdi_FETCH-LOGICAL-c629t-2578e83c52b6bc3434b99b9b6c023b7a9f560266739b19ba406250a6d221891a3
container_end_page 3976
container_issue 16
container_start_page 3971
container_title Blood advances
container_volume 4
creator Schrottmaier, Waltraud C.
Salzmann, Manuel
Badrnya, Sigrun
Mussbacher, Marion
Kral-Pointner, Julia B.
Morava, Susanne
Pirabe, Anita
Brunnthaler, Laura
Yaiw, Koon C.
Heber, Ulrike M.
Pereyra, David
Andersen, Jan T.
Bergthaler, Andreas
Söderberg-Nauclér, Cecilia
Karlsson, Mikael C.I.
Assinger, Alice
Forsell, Mattias N.E.
description •Platelets contain virus-specific IgGs that potently diminish viral infection in vitro and in vivo.•Release of platelet IgG is more efficient at virus neutralization than equal amounts of plasma IgG. [Display omitted]
doi_str_mv 10.1182/bloodadvances.2020001786
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source NORA - Norwegian Open Research Archives; ScienceDirect®; PubMed Central
subjects Blood Platelets
Medicin och hälsovetenskap
Stimulus Report
Viruses
title Platelets mediate serological memory to neutralize viruses in vitro and in vivo
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