High-normal blood pressure conferred higher risk of cardiovascular disease in a random population sample of 50-year-old men: A 21-year follow-up

• Published in: Medicine (Baltimore) 2020-04, Vol.99 (17), p.e19895-e19895
• Main Authors: Chen, Xiaojing, Barywani, Salim Bary, Hansson, Per-Olof, Rosengren, Annika, Thunström, Erik, Zhong, You, Ergatoudes, Constantinos, Mandalenakis, Zacharias, Caidahl, Kenneth, Fu, Michael
• Format: Article
• Language: English
• Subjects: Analysis of Variance; Blood Pressure - physiology; Cardiac and Cardiovascular Systems; Cardiovascular Diseases - classification; Cardiovascular Diseases - epidemiology; Cohort Studies; Follow-Up Studies; Heart Failure - classification; Heart Failure - epidemiology; Humans; Kardiologi; Male; Medicin och hälsovetenskap; Middle Aged; Myocardial Infarction - classification; Myocardial Infarction - epidemiology; Observational Study; Proportional Hazards Models; Prospective Studies; Registries - statistics & numerical data; Risk Factors; Surveys and Questionnaires; Sweden - epidemiology
• ISSN: 0025-7974; 1536-5964; 1536-5964
• DOI: 10.1097/MD.0000000000019895

The relationship between various categories of blood pressure (BP), subtypes of hypertension, and development of cardiovascular disease (CVD) have not been extensively studied. Therefore, our study aimed to explore this relationship in a random population sample of men born in 1943, living in Sweden and followed over a 21-year period.Participants were examined for the first time in 1993 (age 50 years), where data on medical history, concomitant diseases, and general health were collected. The examination was repeated in 2003 and with additional echocardiography also in 2014. Classification of participants according to their BP at the age of 50 years was as follows: optimal-normal BP (systolic blood pressure [SBP]