Effects of Sex on Early Outcome following Repair of Acute Type A Aortic Dissection: Results from The Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD)

• Published in: Aorta (Stamford, Conn.) Conn.), 2019-02, Vol.7 (1), p.007-014
• Main Authors: Chemtob, Raphaelle A., Hjortdal, Vibeke, Ahlsson, Anders, Gunn, Jarmo, Mennander, Ari, Zindovic, Igor, Olsson, Christian, Pivodic, Aldina, Hansson, Emma C., Jeppsson, Anders, Geirsson, Arnar, Gudbjartsson, Tomas
• Format: Article
• Language: English
• Subjects: aortic dissection; aortic operation; Cardiac and Cardiovascular Systems; Clinical Medicine; complications; Kardiologi; Klinisk medicin; Medical and Health Sciences; Medicin och hälsovetenskap; Original; Original Research Article; outcomes; sex; surgery
• ISSN: 2325-4637; 2325-4637
• DOI: 10.1055/s-0039-1687900

Abstract Background  Female sex is known to have increased perioperative mortality in cardiac surgery. Studies reporting effects of sex on outcome following surgical repair for acute Type A aortic dissection (ATAAD) have been limited by small cohorts of heterogeneous patient populations and have shown diverging results. This study aimed to compare perioperative characteristics, operative management, and postoperative outcome between sexes in a large and well-defined cohort of patients operated for ATAAD. Methods  The Nordic Consortium for Acute Type A Aortic Dissection study included patients with surgical repair of ATAAD at eight Nordic centers between January 2005 and December 2014. Independent predictors of 30-day mortality were identified using multivariable logistic regression. Results  Females represented 373 (32%) out of 1,154 patients and were significantly older (65 ± 11 vs. 60 ± 12 years, p