Loading…
Meta‐analysis of risk factors and complications associated with atrial fibrillation after oesophagectomy
Background Oesophagectomy is associated with high morbidity and mortality rates. New‐onset atrial fibrillation (AF) is a frequent complication following oesophagectomy. Several studies have explored whether new‐onset AF is associated with adverse events after oesophagectomy. Methods This review was...
Saved in:
Published in: | British journal of surgery 2019-04, Vol.106 (5), p.534-547 |
---|---|
Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c3798-6f6b8eb189b1be69ed3c0c9a9e832137b5efc8bc2f72df84991664d537522313 |
---|---|
cites | |
container_end_page | 547 |
container_issue | 5 |
container_start_page | 534 |
container_title | British journal of surgery |
container_volume | 106 |
creator | Schizas, D. Kosmopoulos, M. Giannopoulos, S. Giannopoulos, S. Kokkinidis, D. G. Karampetsou, N. Papanastasiou, C. A. Rouvelas, I. Liakakos, T. |
description | Background
Oesophagectomy is associated with high morbidity and mortality rates. New‐onset atrial fibrillation (AF) is a frequent complication following oesophagectomy. Several studies have explored whether new‐onset AF is associated with adverse events after oesophagectomy.
Methods
This review was performed according to PRISMA guidelines. Eligible studies were identified through a search of PubMed, Scopus and Cochrane CENTRAL databases up to 25 November 2018. A meta‐analysis was conducted with the use of random‐effects modelling. The I2 statistic was used to assess for heterogeneity.
Results
In total, 53 studies including 9087 patients were eligible for analysis. The overall incidence of postoperative AF was 16·5 per cent. Coronary artery disease and hypertension were associated with AF, whereas diabetes, smoking and chronic obstructive pulmonary disease were not. Patients with AF had a significantly higher risk of overall postoperative adverse events than those without fibrillation (odds ratio (OR) 5·50, 95 per cent c.i. 3·51 to 8·30), including 30‐day mortality (OR 2·49, 1·70 to 3·64), anastomotic leak (OR 2·65, 1·53 to 4·59) and pneumonia (OR 3·42, 2·39 to 4·90).
Conclusion
Postoperative AF is frequently observed in patients undergoing oesophagectomy for cancer. It is associated with an increased risk of death and postoperative complications.
This meta‐analysis assessed risk factors and clinical significance of the development of new‐onset postoperative atrial fibrillation after oesophagectomy. History of coronary artery disease and hypertension increased the risk of new‐onset postoperative atrial fibrillation. Postoperative atrial fibrillation was associated with increased overall mortality, increased risk of an anastomotic leak and increased risk of postoperative pneumonia.
Bad news |
doi_str_mv | 10.1002/bjs.11128 |
format | article |
fullrecord | <record><control><sourceid>proquest_swepu</sourceid><recordid>TN_cdi_swepub_primary_oai_swepub_ki_se_481039</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2197886881</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3798-6f6b8eb189b1be69ed3c0c9a9e832137b5efc8bc2f72df84991664d537522313</originalsourceid><addsrcrecordid>eNp1kcFOHDEMhqOqVdnSHniBKsdeBuJkJ5McWwQURNVDuUdJxoEsM5vpZFarvfEIfcY-CWF3gRMnW_b325Z_Qo6AHQNj_MQt8jEAcPWOzEDIuuIg1XsyY4w1FQguDsinnBeMgWA1_0gOBNNMSeAzsviFk_3_8M8ubbfJMdMU6BjzPQ3WT2nM1C5b6lM_dNHbKaZlqeScfLQTtnQdpztqpzHajoboxth1W4jaMOFIE-Y03NlbLKP6zWfyIdgu45d9PCQ352c3pz-r698Xl6ffrysvGq0qGaRT6EBpBw6lxlZ45rXVqAQH0bgag1fO89DwNqi51iDlvK1FU3MuQBySajc2r3FYOTOMsbfjxiQbzb50XzI0cwVM6MLrN_lhTO2r6FkIc1Y35XuyaL_ttAX8u8I8mT5mj-ULS0yrbDjoRimp1NNZX_foyvXYvqx5tqIAJztgHTvcvPSBmSePTfHYbD02P67-bBPxCIYanQU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2197886881</pqid></control><display><type>article</type><title>Meta‐analysis of risk factors and complications associated with atrial fibrillation after oesophagectomy</title><source>Oxford Journals Online</source><creator>Schizas, D. ; Kosmopoulos, M. ; Giannopoulos, S. ; Giannopoulos, S. ; Kokkinidis, D. G. ; Karampetsou, N. ; Papanastasiou, C. A. ; Rouvelas, I. ; Liakakos, T.</creator><creatorcontrib>Schizas, D. ; Kosmopoulos, M. ; Giannopoulos, S. ; Giannopoulos, S. ; Kokkinidis, D. G. ; Karampetsou, N. ; Papanastasiou, C. A. ; Rouvelas, I. ; Liakakos, T.</creatorcontrib><description>Background
Oesophagectomy is associated with high morbidity and mortality rates. New‐onset atrial fibrillation (AF) is a frequent complication following oesophagectomy. Several studies have explored whether new‐onset AF is associated with adverse events after oesophagectomy.
Methods
This review was performed according to PRISMA guidelines. Eligible studies were identified through a search of PubMed, Scopus and Cochrane CENTRAL databases up to 25 November 2018. A meta‐analysis was conducted with the use of random‐effects modelling. The I2 statistic was used to assess for heterogeneity.
Results
In total, 53 studies including 9087 patients were eligible for analysis. The overall incidence of postoperative AF was 16·5 per cent. Coronary artery disease and hypertension were associated with AF, whereas diabetes, smoking and chronic obstructive pulmonary disease were not. Patients with AF had a significantly higher risk of overall postoperative adverse events than those without fibrillation (odds ratio (OR) 5·50, 95 per cent c.i. 3·51 to 8·30), including 30‐day mortality (OR 2·49, 1·70 to 3·64), anastomotic leak (OR 2·65, 1·53 to 4·59) and pneumonia (OR 3·42, 2·39 to 4·90).
Conclusion
Postoperative AF is frequently observed in patients undergoing oesophagectomy for cancer. It is associated with an increased risk of death and postoperative complications.
This meta‐analysis assessed risk factors and clinical significance of the development of new‐onset postoperative atrial fibrillation after oesophagectomy. History of coronary artery disease and hypertension increased the risk of new‐onset postoperative atrial fibrillation. Postoperative atrial fibrillation was associated with increased overall mortality, increased risk of an anastomotic leak and increased risk of postoperative pneumonia.
Bad news</description><identifier>ISSN: 0007-1323</identifier><identifier>ISSN: 1365-2168</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1002/bjs.11128</identifier><identifier>PMID: 30908612</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>Medicin och hälsovetenskap</subject><ispartof>British journal of surgery, 2019-04, Vol.106 (5), p.534-547</ispartof><rights>2019 BJS Society Ltd Published by John Wiley & Sons Ltd</rights><rights>2019 BJS Society Ltd Published by John Wiley & Sons Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3798-6f6b8eb189b1be69ed3c0c9a9e832137b5efc8bc2f72df84991664d537522313</citedby><orcidid>0000-0002-7046-0112</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30908612$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:140576126$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Schizas, D.</creatorcontrib><creatorcontrib>Kosmopoulos, M.</creatorcontrib><creatorcontrib>Giannopoulos, S.</creatorcontrib><creatorcontrib>Giannopoulos, S.</creatorcontrib><creatorcontrib>Kokkinidis, D. G.</creatorcontrib><creatorcontrib>Karampetsou, N.</creatorcontrib><creatorcontrib>Papanastasiou, C. A.</creatorcontrib><creatorcontrib>Rouvelas, I.</creatorcontrib><creatorcontrib>Liakakos, T.</creatorcontrib><title>Meta‐analysis of risk factors and complications associated with atrial fibrillation after oesophagectomy</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>Background
Oesophagectomy is associated with high morbidity and mortality rates. New‐onset atrial fibrillation (AF) is a frequent complication following oesophagectomy. Several studies have explored whether new‐onset AF is associated with adverse events after oesophagectomy.
Methods
This review was performed according to PRISMA guidelines. Eligible studies were identified through a search of PubMed, Scopus and Cochrane CENTRAL databases up to 25 November 2018. A meta‐analysis was conducted with the use of random‐effects modelling. The I2 statistic was used to assess for heterogeneity.
Results
In total, 53 studies including 9087 patients were eligible for analysis. The overall incidence of postoperative AF was 16·5 per cent. Coronary artery disease and hypertension were associated with AF, whereas diabetes, smoking and chronic obstructive pulmonary disease were not. Patients with AF had a significantly higher risk of overall postoperative adverse events than those without fibrillation (odds ratio (OR) 5·50, 95 per cent c.i. 3·51 to 8·30), including 30‐day mortality (OR 2·49, 1·70 to 3·64), anastomotic leak (OR 2·65, 1·53 to 4·59) and pneumonia (OR 3·42, 2·39 to 4·90).
Conclusion
Postoperative AF is frequently observed in patients undergoing oesophagectomy for cancer. It is associated with an increased risk of death and postoperative complications.
This meta‐analysis assessed risk factors and clinical significance of the development of new‐onset postoperative atrial fibrillation after oesophagectomy. History of coronary artery disease and hypertension increased the risk of new‐onset postoperative atrial fibrillation. Postoperative atrial fibrillation was associated with increased overall mortality, increased risk of an anastomotic leak and increased risk of postoperative pneumonia.
Bad news</description><subject>Medicin och hälsovetenskap</subject><issn>0007-1323</issn><issn>1365-2168</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp1kcFOHDEMhqOqVdnSHniBKsdeBuJkJ5McWwQURNVDuUdJxoEsM5vpZFarvfEIfcY-CWF3gRMnW_b325Z_Qo6AHQNj_MQt8jEAcPWOzEDIuuIg1XsyY4w1FQguDsinnBeMgWA1_0gOBNNMSeAzsviFk_3_8M8ubbfJMdMU6BjzPQ3WT2nM1C5b6lM_dNHbKaZlqeScfLQTtnQdpztqpzHajoboxth1W4jaMOFIE-Y03NlbLKP6zWfyIdgu45d9PCQ352c3pz-r698Xl6ffrysvGq0qGaRT6EBpBw6lxlZ45rXVqAQH0bgag1fO89DwNqi51iDlvK1FU3MuQBySajc2r3FYOTOMsbfjxiQbzb50XzI0cwVM6MLrN_lhTO2r6FkIc1Y35XuyaL_ttAX8u8I8mT5mj-ULS0yrbDjoRimp1NNZX_foyvXYvqx5tqIAJztgHTvcvPSBmSePTfHYbD02P67-bBPxCIYanQU</recordid><startdate>201904</startdate><enddate>201904</enddate><creator>Schizas, D.</creator><creator>Kosmopoulos, M.</creator><creator>Giannopoulos, S.</creator><creator>Giannopoulos, S.</creator><creator>Kokkinidis, D. G.</creator><creator>Karampetsou, N.</creator><creator>Papanastasiou, C. A.</creator><creator>Rouvelas, I.</creator><creator>Liakakos, T.</creator><general>John Wiley & Sons, Ltd</general><scope>NPM</scope><scope>7X8</scope><scope>ADTPV</scope><scope>AOWAS</scope><orcidid>https://orcid.org/0000-0002-7046-0112</orcidid></search><sort><creationdate>201904</creationdate><title>Meta‐analysis of risk factors and complications associated with atrial fibrillation after oesophagectomy</title><author>Schizas, D. ; Kosmopoulos, M. ; Giannopoulos, S. ; Giannopoulos, S. ; Kokkinidis, D. G. ; Karampetsou, N. ; Papanastasiou, C. A. ; Rouvelas, I. ; Liakakos, T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3798-6f6b8eb189b1be69ed3c0c9a9e832137b5efc8bc2f72df84991664d537522313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Medicin och hälsovetenskap</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schizas, D.</creatorcontrib><creatorcontrib>Kosmopoulos, M.</creatorcontrib><creatorcontrib>Giannopoulos, S.</creatorcontrib><creatorcontrib>Giannopoulos, S.</creatorcontrib><creatorcontrib>Kokkinidis, D. G.</creatorcontrib><creatorcontrib>Karampetsou, N.</creatorcontrib><creatorcontrib>Papanastasiou, C. A.</creatorcontrib><creatorcontrib>Rouvelas, I.</creatorcontrib><creatorcontrib>Liakakos, T.</creatorcontrib><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>SwePub</collection><collection>SwePub Articles</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schizas, D.</au><au>Kosmopoulos, M.</au><au>Giannopoulos, S.</au><au>Giannopoulos, S.</au><au>Kokkinidis, D. G.</au><au>Karampetsou, N.</au><au>Papanastasiou, C. A.</au><au>Rouvelas, I.</au><au>Liakakos, T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Meta‐analysis of risk factors and complications associated with atrial fibrillation after oesophagectomy</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>2019-04</date><risdate>2019</risdate><volume>106</volume><issue>5</issue><spage>534</spage><epage>547</epage><pages>534-547</pages><issn>0007-1323</issn><issn>1365-2168</issn><eissn>1365-2168</eissn><abstract>Background
Oesophagectomy is associated with high morbidity and mortality rates. New‐onset atrial fibrillation (AF) is a frequent complication following oesophagectomy. Several studies have explored whether new‐onset AF is associated with adverse events after oesophagectomy.
Methods
This review was performed according to PRISMA guidelines. Eligible studies were identified through a search of PubMed, Scopus and Cochrane CENTRAL databases up to 25 November 2018. A meta‐analysis was conducted with the use of random‐effects modelling. The I2 statistic was used to assess for heterogeneity.
Results
In total, 53 studies including 9087 patients were eligible for analysis. The overall incidence of postoperative AF was 16·5 per cent. Coronary artery disease and hypertension were associated with AF, whereas diabetes, smoking and chronic obstructive pulmonary disease were not. Patients with AF had a significantly higher risk of overall postoperative adverse events than those without fibrillation (odds ratio (OR) 5·50, 95 per cent c.i. 3·51 to 8·30), including 30‐day mortality (OR 2·49, 1·70 to 3·64), anastomotic leak (OR 2·65, 1·53 to 4·59) and pneumonia (OR 3·42, 2·39 to 4·90).
Conclusion
Postoperative AF is frequently observed in patients undergoing oesophagectomy for cancer. It is associated with an increased risk of death and postoperative complications.
This meta‐analysis assessed risk factors and clinical significance of the development of new‐onset postoperative atrial fibrillation after oesophagectomy. History of coronary artery disease and hypertension increased the risk of new‐onset postoperative atrial fibrillation. Postoperative atrial fibrillation was associated with increased overall mortality, increased risk of an anastomotic leak and increased risk of postoperative pneumonia.
Bad news</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>30908612</pmid><doi>10.1002/bjs.11128</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0002-7046-0112</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0007-1323 |
ispartof | British journal of surgery, 2019-04, Vol.106 (5), p.534-547 |
issn | 0007-1323 1365-2168 1365-2168 |
language | eng |
recordid | cdi_swepub_primary_oai_swepub_ki_se_481039 |
source | Oxford Journals Online |
subjects | Medicin och hälsovetenskap |
title | Meta‐analysis of risk factors and complications associated with atrial fibrillation after oesophagectomy |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T02%3A43%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_swepu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Meta%E2%80%90analysis%20of%20risk%20factors%20and%20complications%20associated%20with%20atrial%20fibrillation%20after%20oesophagectomy&rft.jtitle=British%20journal%20of%20surgery&rft.au=Schizas,%20D.&rft.date=2019-04&rft.volume=106&rft.issue=5&rft.spage=534&rft.epage=547&rft.pages=534-547&rft.issn=0007-1323&rft.eissn=1365-2168&rft_id=info:doi/10.1002/bjs.11128&rft_dat=%3Cproquest_swepu%3E2197886881%3C/proquest_swepu%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3798-6f6b8eb189b1be69ed3c0c9a9e832137b5efc8bc2f72df84991664d537522313%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2197886881&rft_id=info:pmid/30908612&rfr_iscdi=true |