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Cancer Core Europe: A European cancer research alliance realizing a research infrastructure with critical mass and programmatic approach to cure cancer in the 21st century

Translational cancer research covers the whole cancer research continuum from basic to preclinical to early clinical, late clinical and outcomes research. Basic-preclinical research is the “engine” for early clinical research bridging the early translational research gap. Cancer Core Europe has been...

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Published in:European journal of cancer (1990) 2018-11, Vol.103, p.155-159
Main Authors: Calvo, Fabien, Apolone, Giovanni, Baumann, Michael, Caldas, Carlos, Celis, Julio E., de Lorenzo, Franceso, Ernberg, Ingemar, Ringborg, Ulrik, Rowell, John, Tabernero, Josep, Voest, Emile, Eggermont, Alexander
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cited_by cdi_FETCH-LOGICAL-c472t-787c340f681b71f049c5e4722e84b6c18d4de29cdaacb1a334b506ea8b9f2a493
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container_title European journal of cancer (1990)
container_volume 103
creator Calvo, Fabien
Apolone, Giovanni
Baumann, Michael
Caldas, Carlos
Celis, Julio E.
de Lorenzo, Franceso
Ernberg, Ingemar
Ringborg, Ulrik
Rowell, John
Tabernero, Josep
Voest, Emile
Eggermont, Alexander
description Translational cancer research covers the whole cancer research continuum from basic to preclinical to early clinical, late clinical and outcomes research. Basic-preclinical research is the “engine” for early clinical research bridging the early translational research gap. Cancer Core Europe has been created to construct a sustainable, high level, shared research infrastructure platform with research collaborations and taskforces (data sharing, clinical trials, genomics, immunotherapy, imaging, legal & ethical problems, and education & training) having representatives from all seven member centres, in a controlled expansion model. In parallel, a consortium of ten cancer prevention centres was established, Cancer Prevention Europe, to support the complete cancer prevention research continuum. Cancer Core Europe is launching at present the Basket of Baskets trial, which is the largest personalized cancer medicine trial effort in Europe. At present, Cancer Core Europe and Cancer Prevention Europe are in the process of integrating therapeutics and prevention strategies to address in partnership the increasing cancer problem. By offering innovative approaches for cancer research, links to the healthcare systems, development of quality-assured multidisciplinary cancer care, as well as the assessment of long-term outcomes, the infrastructure is expected to serve as a hub to connect with other centres in Europe as well as on other continents. In this manner Cancer Core Europe and Cancer Prevention Europe prepare to tackle the “Mission on Cancer”, with infrastructure and proofs of concept for therapeutics and prevention, research for assessment of effectiveness, health economics and added value for patients and the healthcare systems.
doi_str_mv 10.1016/j.ejca.2018.08.023
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subjects 21st century
Alliance
Baskets
Cancer
Cancer research
Cancer therapies
Clinical trials
Collaboration
Consortia
Critical mass
Data retrieval
Delivery of Health Care - methods
Ethical standards
Europe
Health care
History, 21st Century
Humans
Immunotherapy
Infrastructure
Innovation
Medical research
Medicin och hälsovetenskap
Neoplasms - pathology
Neoplasms - therapy
Oncology
Oncopolicy
Precision Medicine - methods
Prevention
Quality assurance
Quality of Health Care - standards
Translation
Translational Medical Research - methods
title Cancer Core Europe: A European cancer research alliance realizing a research infrastructure with critical mass and programmatic approach to cure cancer in the 21st century
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