Prognostic value of routinely available data in patients with stable coronary heart disease. A 10-year follow-up of patients sampled at random times during their disease course

ObjectiveTo characterise the long-term prognosis of patients with stable coronary artery heart disease by means of ‘standard predictors’ defined as demographic, clinical and biochemical quantities routinely available in general practices and ascertained at an interview not prompted by renewed cardia...

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Published in:Open heart 2018, Vol.5 (2), p.e000808-e000808
Main Authors: Winkel, Per, Jakobsen, Janus Christian, Hilden, Jørgen, Jensen, Gorm, Kjøller, Erik, Sajadieh, Ahmad, Kastrup, Jens, Kolmos, Hans Jørn, Larsson, Anders, Ärnlöv, Johan, Gluud, Christian
Format: Article
Language:English
Subjects:
Angina pectoris
Angioplasty
Cardiology
Cardiovascular disease
CLARICOR
Coronary Artery Disease
Coronary vessels
Diabetes
Health and Welfare
Health risk assessment
Heart attacks
Heart failure
Hypertension
Hälsa och välfärd
ischaemic heart disease
Medical prognosis
Medicin och hälsovetenskap
Mortality
Patients
predictors
Survival analysis
Task forces
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Summary:ObjectiveTo characterise the long-term prognosis of patients with stable coronary artery heart disease by means of ‘standard predictors’ defined as demographic, clinical and biochemical quantities routinely available in general practices and ascertained at an interview not prompted by renewed cardiac complaints.MethodsThis is an observational study based on data from 2199 Copenhagen placebo patients from the ‘clarithromycin for patients with stable coronary heart disease’ trial of patients with stable coronary heart disease. In the trial, we compared the effects of 14 days of clarithromycin treatment versus placebo. The predictors were based on the interview forms and blood samples collected at entry, along with demographic information from hospital files.We studied ‘standard predictors’ of a composite outcome (myocardial infarction, unstable angina, cerebrovascular disease or all-cause death) and of all-cause death. Using Cox regression, we compared predictions of status at 3, 6 and 9 years without and with the use of ‘standard predictors’ and used receiver operating characteristic statistic.ResultsFew ‘standard predictors’ were associated (p
ISSN:2053-3624
2398-595X
2053-3624
DOI:10.1136/openhrt-2018-000808