The roles for innate lymphoid cells in the human immune system

From constituting a novel and obscure cell population, innate lymphoid cells (ILCs) are now accepted as a self-evident part of the immune system, contributing with unique and complementary functions to immunity by production of effector cytokines and interaction with other cell types. In this review...

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Bibliographic Details
Published in:Seminars in immunopathology 2018-07, Vol.40 (4), p.407-419
Main Authors: Mazzurana, L., Rao, A., Van Acker, A., Mjösberg, J.
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Immune system
Immunology
Internal Medicine
Lymphoid cells
Medicin och hälsovetenskap
Plastics
Review
Xenotransplantation
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Summary:From constituting a novel and obscure cell population, innate lymphoid cells (ILCs) are now accepted as a self-evident part of the immune system, contributing with unique and complementary functions to immunity by production of effector cytokines and interaction with other cell types. In this review, we discuss the redundant and complementary roles of the highly plastic human ILCs and their interaction with other immune cells with the ultimate aim of placing ILCs in a wider context within the human immune system.
ISSN:1863-2297
1863-2300
1863-2300
DOI:10.1007/s00281-018-0688-7