β-Blocker after severe traumatic brain injury is associated with better long-term functional outcome: a matched case control study

Purpose Severe traumatic brain injury (TBI) is the predominant cause of death and disability following trauma. Several studies have observed improved survival in TBI patients exposed to β-blockers, however, the effect on functional outcome is poorly documented. Methods Adult patients with severe TBI...

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Bibliographic Details
Published in:European journal of trauma and emergency surgery (Munich : 2007) 2017-12, Vol.43 (6), p.783-789
Main Authors: Ahl, R., Thelin, E. P., Sjölin, G., Bellander, B.-M., Riddez, L., Talving, P., Mohseni, S.
Format: Article
Language:English
Subjects:
Adrenergic beta-Antagonists - administration & dosage
Adrenergic beta-Antagonists - therapeutic use
Brain Injuries, Traumatic - drug therapy
Brain Injuries, Traumatic - mortality
Brain Injuries, Traumatic - rehabilitation
Case-Control Studies
Critical Care Medicine
Emergency Medicine
Female
Glasgow Coma Scale
Humans
Injury Severity Score
Intensive
Kirurgi
Length of Stay
Male
Medicin och hälsovetenskap
Medicine
Medicine & Public Health
Middle Aged
Original
Original Article
Recovery of Function
Sports Medicine
Surgery
Surgical Orthopedics
Survival Analysis
Sweden
Traumatic brain injury
Traumatic Surgery
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Summary:Purpose Severe traumatic brain injury (TBI) is the predominant cause of death and disability following trauma. Several studies have observed improved survival in TBI patients exposed to β-blockers, however, the effect on functional outcome is poorly documented. Methods Adult patients with severe TBI (head AIS ≥ 3) were identified from a prospectively collected TBI database over a 5-year period. Patients with neurosurgical ICU length of stay
ISSN:1863-9933
1863-9941
1863-9941
DOI:10.1007/s00068-017-0779-5