Relationship between depression and diabetes in pregnancy: A systematic review

AIM To systematically review the literature on women with both diabetes in pregnancy (DIP) and depression during or after pregnancy.METHODS In this systematic literature review, PubMed/MEDLINE and EMBASE were searched (13 November 2015) using terms for diabetes (type 1, type 2, or gestational), depr...

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Bibliographic Details
Published in:World journal of diabetes 2016-11, Vol.7 (19), p.554-571
Main Authors: Ross, Glynis P, Falhammar, Henrik, Chen, Roger, Barraclough, Helen, Kleivenes, Ole, Gallen, Ian
Format: Article
Language:English
Subjects:
care
Depression
depression
Depressive
Diabetes
disorder
Gestational
Medicin och hälsovetenskap
mellitus
Perinatal
Postnatal
Postpartum
Pregnancy
Systematic Reviews
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Summary:AIM To systematically review the literature on women with both diabetes in pregnancy (DIP) and depression during or after pregnancy.METHODS In this systematic literature review, PubMed/MEDLINE and EMBASE were searched (13 November 2015) using terms for diabetes (type 1, type 2, or gestational), depression,and pregnancy (no language or date restrictions).Publications that reported on women who had both DIP (any type) and depression or depressive symptoms before, during, or within one year after pregnancy were considered for inclusion. All study types were eligible for inclusion; conference abstracts, narrative reviews,nonclinical letters, editorials, and commentaries were excluded, unless they provided treatment guidance.RESULTS Of 1189 articles identified, 48 articles describing women with both DIP and depression were included (sample sizes 36 to > 32 million). Overall study quality was poor;most studies were observational, and only 12 studies (mostly retrospective database studies) required clinical depression diagnosis. The prevalence of concurrent DIP (any type) and depression in general populations of pregnant women ranged from 0% to 1.6% (median 0.61%; 12 studies). The prevalence of depression among women with gestational diabetes ranged from 4.1% to 80% (median 14.7%; 16 studies). Many studies examined whether DIP was a risk factor for depression or depression was a risk factor for DIP. However, there was no clear consensus for either relationship. Importantly, we found limited guidance on the management of women with both DIP and depression.CONCLUSION Given the increasing prevalence of diabetes and depression,high-quality research and specific guidance for management of pregnant women with both conditions are warranted.
ISSN:1948-9358
1948-9358
DOI:10.4239/wjd.v7.i19.554