Does Coronary Angiography and Percutaneous Coronary Intervention Affect Cognitive Function?

Cerebral microemboli are frequently observed during coronary angiography (CA) and percutaneous coronary intervention (PCI), and their numbers have been related to the vascular access site used. Although cerebral microemboli can cause silent cerebral lesions, their clinical impact is debated. To stud...

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Bibliographic Details
Published in:The American journal of cardiology 2016-11, Vol.118 (10), p.1437-1441
Main Authors: Jurga, Juliane, MD, PhD, Tornvall, Per, MD, PhD, Dey, Linda, MD, van der Linden, Jan, MD, PhD, Sarkar, Nondita, MD, PhD, von Euler, Mia, MD, PhD
Format: Article
Language:English
Subjects:
Aged
Angina pectoris
Angina, Stable - diagnosis
Angina, Stable - psychology
Angina, Stable - surgery
Cardiovascular
Cardiovascular disease
Catheters
Cognition - physiology
Cognition Disorders - physiopathology
Cognition Disorders - psychology
Cognitive ability
Coronary Angiography - psychology
Female
Follow-Up Studies
Heart failure
Humans
Male
Medical imaging
Medicin och hälsovetenskap
Neuropsychological Tests
Patients
Percutaneous Coronary Intervention - psychology
Prognosis
Retrospective Studies
Risk Factors
Stroke
Studies
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Summary:Cerebral microemboli are frequently observed during coronary angiography (CA) and percutaneous coronary intervention (PCI), and their numbers have been related to the vascular access site used. Although cerebral microemboli can cause silent cerebral lesions, their clinical impact is debated. To study this, 93 patients referred for CA or PCI underwent serial cognitive testing using the Montreal Cognitive Assessment (MoCA) test to detect postprocedural cognitive impairment. Patients were randomized to radial or femoral access. In a subgroup of 35 patients, the number of cerebral microemboli was monitored with transcranial Doppler technique. We found the median precatheterization result of the MoCA test to be 27, and it did not change significantly 4 and 31 days, respectively, after the procedure. There was no significant correlation between the number of cerebral microemboli and the difference between preprocedural and postprocedural MoCA tests. The test results did not differ between vascular access sites. One-third of the patients had a precatheterization median MoCA test result
ISSN:0002-9149
1879-1913
1879-1913
DOI:10.1016/j.amjcard.2016.08.003