Unaltered pneumococcal carriage prevalence due to expansion of non-vaccine types of low invasive potential 8 years after vaccine introduction in Stockholm, Sweden

Highlights • 94% of pneumococcal carriage strains were of non-vaccine serotypes 8 years post-PCV. • Low invasive disease potential for most emerging non-vaccine types in carriage. • High invasive disease potential for non-vaccine serotypes 22F, 8, 12F and 9N. • No change in antibiotic resistance amo...

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Bibliographic Details
Published in:Vaccine 2016-08, Vol.34 (38), p.4565-4571
Main Authors: Lindstrand, Ann, Galanis, Ilias, Darenberg, Jessica, Morfeldt, Eva, Naucler, Pontus, Blennow, Margareta, Alfvén, Tobias, Henriques-Normark, Birgitta, Örtqvist, Åke
Format: Article
Language:English
Subjects:
Allergy and Immunology
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Summary:Highlights • 94% of pneumococcal carriage strains were of non-vaccine serotypes 8 years post-PCV. • Low invasive disease potential for most emerging non-vaccine types in carriage. • High invasive disease potential for non-vaccine serotypes 22F, 8, 12F and 9N. • No change in antibiotic resistance among pneumococcal isolates after PCV introduction.
ISSN:0264-410X
DOI:10.1016/j.vaccine.2016.07.031