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Association of thalassemia major and gingival inflammation: A pilot study
Highlights • We hypothesized that thalassemia major may affect levels of MMPs biofluids and thereby deteriorate clinical periodontal status. • We examine changes in the level of MMPs in thalassemia major patients. • Thalassemia major may exacerbate the local inflammatory response. • Higher serum TIM...
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Published in: | Archives of oral biology 2016-04, Vol.64, p.80-84 |
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container_title | Archives of oral biology |
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creator | Gümüş, Pınar Kahraman-Çeneli, Selda Akcali, Aliye Sorsa, Timo Tervahartiala, Taina Buduneli, Nurcan Özçaka, Özgün |
description | Highlights • We hypothesized that thalassemia major may affect levels of MMPs biofluids and thereby deteriorate clinical periodontal status. • We examine changes in the level of MMPs in thalassemia major patients. • Thalassemia major may exacerbate the local inflammatory response. • Higher serum TIMP-1 levels in thalassemia major could be result of their systemic drug usage. |
doi_str_mv | 10.1016/j.archoralbio.2015.12.008 |
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subjects | Adolescent Adult Advanced Basic Science beta-Thalassemia - blood beta-Thalassemia - enzymology beta-Thalassemia - pathology Cross-Sectional Studies Dental Plaque Index Dentistry Female Fluoroimmunoassay - methods Gingiva Gingival Crevicular Fluid - enzymology Gingivitis - blood Gingivitis - enzymology Gingivitis - pathology Humans Inflammation Male Matrix metalloproteinase 8 Matrix Metalloproteinase 8 - analysis Matrix Metalloproteinase 8 - blood Matrix metalloproteinase 9 Matrix Metalloproteinase 9 - analysis Matrix Metalloproteinase 9 - blood Medicin och hälsovetenskap Middle Aged Periodontal Attachment Loss Periodontal Index Periodontal Pocket Pilot Projects Saliva - chemistry Saliva - enzymology Thalassemia major Tissue inhibitor of metalloproteinase-1 Tissue Inhibitor of Metalloproteinase-1 - analysis Tissue Inhibitor of Metalloproteinase-1 - blood Young Adult |
title | Association of thalassemia major and gingival inflammation: A pilot study |
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