'Multiple-test' approach to the laboratory diagnosis of tuberculosis -perception of medical doctors from Ujjain, India

• Published in: BMC infectious diseases 2015-08, Vol.15 (1), p.322-322, Article 322
• Main Authors: Purohit, Manju Raj, Sharma, Megha, Rosales-Klintz, Senia, Lundborg, Cecilia Stålsby
• Format: Article
• Language: English
• Subjects: Adult; Analysis; Attitude of Health Personnel; Care and treatment; Clinical Laboratory Techniques - standards; Complications and side effects; Diagnosis; Diagnostic Tests, Routine - standards; Female; Health Services Needs and Demand; Humans; India; Interviews as Topic; Male; Medical tests; Medicin och hälsovetenskap; Middle Aged; Patient outcomes; Practice Patterns, Physicians' - statistics & numerical data; Tuberculosis; Tuberculosis, Pulmonary - diagnosis
• ISSN: 1471-2334; 1471-2334
• DOI: 10.1186/s12879-015-1037-2

Delay in diagnosis is one of the most important factors for the control of tuberculosis (TB) in endemic countries like India. As laboratory diagnosis is the mainstay for identification of active disease, we aim to explore and understand the opinions of medical doctors about the laboratory diagnosis of TB in Ujjain, India. Sixteen qualified specialist medical doctors from Ujjain were purposefully selected for the study. Individual interviews with the doctors (13 men and 3 women), were conducted. As one interview could not be completed, data from 15 interviews were analyzed using manifest and latent content analysis. Based on perception of the doctors, the theme; 'challenges and need for the laboratory diagnosis of TB' emerged from the following subthemes: (i) Relationship between basic element of the TB diseases process such as 'Symptoms prior to diagnoses' and 'Clinical characteristics of TB', which were not specific enough to diagnose TB (ii) The prevailing conditions such as lack of explicit diagnostic tools, lead to the doctors using the 'multiple tests' or 'empiric treatment' approach (iii) The doctors proposed that there is a need for access to a rapid, single and simple diagnostic test, and a need for awareness and knowledge of the practitioners regarding specific TB investigations, and early referral to improve the situation at resource-limited settings. The medical specialists use a 'multiple test' or 'empiric treatment' approach to diagnose TB. According to the participants, there is a low dependence and uptake of the available laboratory TB investigations by medical practitioners. There is an urgent need to have a specific, simple and reliable test, and a protocol, to improve diagnosis of TB and to prevent development of resistant TB.