In vivo evidence for neuroplasticity in older adults

Highlights • Most studies of neuroplasticity have been done ex vivo. • In vivo neuroplastic changes were recently shown in young adults using VEPs. • Here, neuroplastic changes in visual cortex were demonstrated in normal old adults. • The N1 component of the VEP was amplified after tetanic visual s...

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Bibliographic Details
Published in:Brain research bulletin 2015-05, Vol.114, p.56-61
Main Authors: Porto, Fábio Henrique de Gobbi, Fox, Anne Murphy, Tusch, Erich S, Sorond, Farzaneh, Mohammed, Abdul H, Daffner, Kirk R
Format: Article
Language:English
Subjects:
Aged
Aging - physiology
Brain - physiology
Electroencephalography
Evoked Potentials, Visual - physiology
Female
Humans
Male
Medicin och hälsovetenskap
Neurology
Neuronal Plasticity - physiology
Neuroplasticity
Neuropsychological Tests
Normal cognitive aging
Photic Stimulation - methods
Principal Component Analysis
Psychology
Psykologi
Signal Processing, Computer-Assisted
Tetanic visual
Visual evoked potentials (VEPs)
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Summary:Highlights • Most studies of neuroplasticity have been done ex vivo. • In vivo neuroplastic changes were recently shown in young adults using VEPs. • Here, neuroplastic changes in visual cortex were demonstrated in normal old adults. • The N1 component of the VEP was amplified after tetanic visual stimulation. • VEPs may enhance the study of age- and disease-related changes in neuroplasticity.
ISSN:0361-9230
1873-2747
1873-2747
DOI:10.1016/j.brainresbull.2015.03.004