Rapid progression of a splenic aneurysm due to segmental arterial mediolysis: A rare cause of acute pancreatitis

Abstract Background The etiology of acute pancreatitis can be manifold, beside the usual causes. We are reporting an unusual cause that triggered acute pancreatitis. Patient & results A 50 year-old male experienced attacks of acute pancreatitis (abdominal pain and elevated amylase and lipase) du...

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Bibliographic Details
Published in:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2013-09, Vol.13 (5), p.553-556
Main Authors: Löhr, J.-Matthias, Dinter, Dietmar, Diehl, Steffen J, Haas, Stephan L, Veeser, Mira, Pfützer, Roland, Retter, Jürgen, Schönberg, Stefan O, Düber, Christoph, Keim, Volker, Schadendorf, Dirk, Witt, Heiko
Format: Article
Language:English
Subjects:
Abdomen
Abdominal Pain - etiology
Acute pancreatitis
Aneurysm - complications
Aneurysm - diagnostic imaging
Aneurysm, Ruptured - complications
Aneurysms
Blood Pressure
Endocrinology & Metabolism
Gastroenterology and Hepatology
Humans
Hypertension
Male
Medicin och hälsovetenskap
Metabolic disorders
Pancreas
Pancreatitis - etiology
Radiography
Radiology, Interventional
Rodents
Segmental arterial mediolysis
Sexual arousal
Sexual Dysfunctions, Psychological - complications
Splenic Artery
Splenic artery aneurysm
Veins & arteries
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Summary:Abstract Background The etiology of acute pancreatitis can be manifold, beside the usual causes. We are reporting an unusual cause that triggered acute pancreatitis. Patient & results A 50 year-old male experienced attacks of acute pancreatitis (abdominal pain and elevated amylase and lipase) during sexual arousal. Serial imaging showed a rapidly-progressing, partly-thrombosed splenic artery aneurysm, with local compression of the pancreas. After angiographic coiling, the attacks subsided. Further angiography revealed additional aneurysms consistent with segmental arterial mediolysis at other sites of the body. Molecular analysis regarding Ehlers–Danlos-syndrome and genetic factors for pancreatitis, autoantibodies and Syphilis serology was negative. Conclusions Acute pancreatitis was triggered by a transient rise in blood pressure during sexual stimulation, which caused rapid progression of a splenic artery aneurysm as part of systemic segmental arterial mediolysis.
ISSN:1424-3903
1424-3911
1424-3911
DOI:10.1016/j.pan.2013.06.001