Portal Venous System Thrombosis After Pancreatic Resection

Background Portal venous system thrombosis (PVST) is a rare, potentially fatal complication after pancreatic resection. The aim of this study was to assess the incidence, presenting symptoms, management, and treatment of PVST in a large cohort of patients. Methods Prospectively collected data on pat...

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Bibliographic Details
Published in:World journal of surgery 2013-01, Vol.37 (1), p.179-184
Main Authors: Ansari, David, Ansorge, Christoph, Andrén-Sandberg, Åke, Ansari, Daniel, Segersvärd, Ralf
Format: Article
Language:English
Subjects:
Abdominal Surgery
Adolescent
Adult
Aged
Aged, 80 and over
Cardiac Surgery
Child
Chronic Pancreatitis
Clinical Medicine
Female
General Surgery
Humans
Incidence
Kirurgi
Klinisk medicin
Male
Medical and Health Sciences
Medicin och hälsovetenskap
Medicine
Medicine & Public Health
Middle Aged
Pancreatectomy - adverse effects
Pancreatic Resection
Portal System
Portal Vein
Portal Vein Thrombosis
Retrospective Studies
Superior Mesenteric Vein
Surgery
Thoracic Surgery
Vascular Surgery
Venous Thrombosis - diagnosis
Venous Thrombosis - epidemiology
Venous Thrombosis - etiology
Venous Thrombosis - therapy
Young Adult
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Summary:Background Portal venous system thrombosis (PVST) is a rare, potentially fatal complication after pancreatic resection. The aim of this study was to assess the incidence, presenting symptoms, management, and treatment of PVST in a large cohort of patients. Methods Prospectively collected data on patients undergoing pancreatic resection between 1997 and 2009 were reviewed retrospectively. Preoperative and postoperative imaging were analyzed for the presence or absence of venous thrombi. All patients received standard thromboprophylaxis with low-molecular-weight heparin (LMWH). Results Of 516 pancreatic resections performed, 18 (3.5 %) were complicated by PVST. The most common clinical presentations were abdominal pain ( n  = 9) and ascites ( n  = 5) but never any alarm symptoms. Other symptoms were vague and nonspecific (e.g., weight loss, fatigue, fever). Total pancreatectomy was a risk factor compared to hemipancreatectomy ( p  
ISSN:0364-2313
1432-2323
1432-2323
DOI:10.1007/s00268-012-1777-8