Hyperglycaemia and cardiovascular disease

. Coronary artery disease and type 2 diabetes are chronic diseases of substantial and growing prevalence. Their coincidence is common, markedly enhancing mortality and morbidity. The risk for cardiovascular disease increases along a spectrum of blood glucose concentrations already apparent at levels...

Full description

Saved in:
Bibliographic Details
Published in:Journal of internal medicine 2007-08, Vol.262 (2), p.145-156
Main Authors: Bartnik, M., Norhammar, A., Rydén, L.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood Glucose - metabolism
Cardiology. Vascular system
Cardiovascular Diseases - etiology
Cardiovascular Diseases - metabolism
Cardiovascular Diseases - mortality
coronary artery disease
Coronary Artery Disease - etiology
Coronary Artery Disease - metabolism
Coronary heart disease
diabetes
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - metabolism
Diabetes Mellitus, Type 2 - mortality
General aspects
Glucose Tolerance Test
Heart
Homeostasis - physiology
Humans
Hyperglycemia - complications
Hyperglycemia - metabolism
impaired glucose tolerance
Insulin Resistance - physiology
Medical sciences
Medicin och hälsovetenskap
Prognosis
Risk Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:. Coronary artery disease and type 2 diabetes are chronic diseases of substantial and growing prevalence. Their coincidence is common, markedly enhancing mortality and morbidity. The risk for cardiovascular disease increases along a spectrum of blood glucose concentrations already apparent at levels regarded as normal. Accordingly, strategies for the early detection of glucometabolic disturbances are needed to find ways to prevent the occurrence of cardiovascular complications or to treat them already at an early stage. More specifically, abnormal glucose tolerance is almost twice as common amongst patients with a myocardial infarction as in population‐based controls and a normal glucose regulation is indeed less common than abnormal glucose metabolism also amongst patients with stable coronary artery disease. Already an abnormal glucose tolerance is a strong risk factor for future cardiovascular events after an acute myocardial infarction. An oral glucose tolerance test should, therefore, be a part of the evaluation of total risk in all patients with coronary artery disease. As glucose disturbances are common and easy to detect, they may be suitable targets for novel secondary preventive efforts.
ISSN:0954-6820
1365-2796
DOI:10.1111/j.1365-2796.2007.01831.x