Early detection of macular changes in patients with diabetes using Rarebit Fovea Test and optical coherence tomography

Aim:To evaluate central retinal thickness and foveal function using optical coherence tomography (OCT) and the Rarebit Fovea Test (RFT) in patients with diabetes without previously known retinopathy or maculopathy.Method:Forty-two patients with diabetes mellitus (DM) were selected from the screening...

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Bibliographic Details
Published in:British journal of ophthalmology 2007-12, Vol.91 (12), p.1596-1598
Main Authors: Nilsson, M, von Wendt, G, Wanger, P, Martin, L
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Diabetes. Impaired glucose tolerance
Diabetic Retinopathy - diagnosis
Diagnostic Techniques, Ophthalmological
Early Diagnosis
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
Fovea Centralis
Humans
Macula Lutea
Male
Medical sciences
Middle Aged
Miscellaneous
Ophthalmology
Retina
Scientific Report
Tomography, Optical Coherence
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Summary:Aim:To evaluate central retinal thickness and foveal function using optical coherence tomography (OCT) and the Rarebit Fovea Test (RFT) in patients with diabetes without previously known retinopathy or maculopathy.Method:Forty-two patients with diabetes mellitus (DM) were selected from the screening records at St Erik Eye Hospital. Inclusion criteria were absence of macular or other retinal changes at previous screening examination and best corrected visual acuity ⩾1.0. These patients and 42 healthy controls were examined with the recently developed RFT, and retinal thickness was measured using OCT. Lens thickness and light scatter were evaluated by Scheimpflug photography.Results:Significantly more DM subjects (12/42) had a subnormal RFT result compared with the controls (2/42) (p = 0.007). None of the 12 DM subjects had maculopathy, one had mild non proliferative diabetic retinopathy, and five had minimal non-proliferative diabetic retinopathy. The retinal thickness in the pericentral zone was significantly (p
ISSN:0007-1161
1468-2079
1468-2079
DOI:10.1136/bjo.2007.124461