Vaccination with genetically modified birch pollen allergens: Immune and clinical effects on oral allergy syndrome

[...]it is possible that certain IgG antibodies may, on binding to the natural allergen, induce a conformational change affecting IgE epitopes.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2007-04, Vol.119 (4), p.1013-1016
Main Authors: Niederberger, Verena, MD, Reisinger, Jürgen, PhD, Valent, Peter, MD, Krauth, Maria-Theresa, MD, Pauli, Gabrielle, MD, van Hage, Marianne, MD, PhD, Cromwell, Oliver, PhD, Horak, Friedrich, MD, Valenta, Rudolf, MD
Format: Article
Language:English
Subjects:
Allergens - administration & dosage
Allergens - genetics
Allergens - immunology
Allergies
Allergy and Immunology
Betula - genetics
Betula - immunology
Binding sites
Derivatives
Double-Blind Method
Experiments
Food
Food Hypersensitivity - immunology
Food Hypersensitivity - therapy
Humans
Immunization
Patients
Plant Proteins - administration & dosage
Plant Proteins - genetics
Plant Proteins - immunology
Pollen
Pollen - genetics
Pollen - immunology
Syndrome
Vaccines, Synthetic - administration & dosage
Vaccines, Synthetic - immunology
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Description
Summary:[...]it is possible that certain IgG antibodies may, on binding to the natural allergen, induce a conformational change affecting IgE epitopes.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2006.12.661