A Meta-Analysis on the Effects of Antibiotic Treatment on Duration of Symptoms Caused by Infection with Campylobacter Species

Eleven randomized, controlled trials of antibiotic treatment versus placebo in patients with Campylobacter species infection were pooled in a meta-analysis. Antibiotic treatment shortened the duration of intestinal symptoms by 1.32 days (95% confidence interval, 0.64-1.99; P < .0001). Because of...

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Bibliographic Details
Published in:Clinical infectious diseases 2007-03, Vol.44 (5), p.696-700
Main Authors: Ternhag, Anders, Asikainen, Tommi, Giesecke, Johan, Ekdahl, Karl
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents - therapeutic use
Antibiotics
Bacteria
Brief Reports
Campylobacter
Campylobacter Infections - diagnosis
Campylobacter Infections - drug therapy
Carrier State
Child
Child, Preschool
Clinical trials
Diarrhea
Drug resistance
Drug Resistance, Bacterial
Epidemiology
Experimentation
Humans
Infant
Infections
Meta analysis
Middle Aged
Operating rooms
Placebo effect
Placebos
Randomized Controlled Trials as Topic
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Summary:Eleven randomized, controlled trials of antibiotic treatment versus placebo in patients with Campylobacter species infection were pooled in a meta-analysis. Antibiotic treatment shortened the duration of intestinal symptoms by 1.32 days (95% confidence interval, 0.64-1.99; P < .0001). Because of problems with drug resistance, a restrictive attitude towards the administration of antibiotics in uncomplicated cases is advised.
ISSN:1058-4838
1537-6591
DOI:10.1086/509924