Studies to assess the long-term efficacy and effectiveness of HPV vaccination in developed and developing countries

We review studies of the implementation of human papillomavirus (HPV) vaccination programmes in developed and developing countries. The review spans the period from establishment of long-term vaccine efficacy follow-up studies, operational research on issues of vaccine preparedness, and relevant pre...

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Bibliographic Details
Published in:Vaccine 2006, Vol.24, p.233
Main Authors: Lehtinen, Matti, Herrero, Rolando, Mayaud, Philippe, Barnabas, Ruanne, Dillner, Joakim, Paavonen, Jorma, Smith, Peter G.
Format: Article
Language:English
Subjects:
Basic Medicine
cervical cancer
effectiveness
efficacy
Medical and Health Sciences
Medicin och hälsovetenskap
Medicinska och farmaceutiska grundvetenskaper
Microbiology in the medical area
Mikrobiologi inom det medicinska området
vaccination
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Summary:We review studies of the implementation of human papillomavirus (HPV) vaccination programmes in developed and developing countries. The review spans the period from establishment of long-term vaccine efficacy follow-up studies, operational research on issues of vaccine preparedness, and relevant predictive modelling studies during the pre-licensure phase to plans of phase IV effectiveness trials, forms of epidemiological surveillance, and further operational research in the post-licensure phase. Much of the research is already ongoing. Depending on the results of the planned immuno bridging studies among HIV-negative and HIV-positive women, further phase III and/or phase IV trials may be warranted. (c) 2006 Elsevier Ltd. All rights reserved.
ISSN:1873-2518
0264-410X
DOI:10.1016/j.vaccine.2006.05.109