Are risk factors for breast cancer similar in women with inflammatory breast cancer and in those with non-inflammatory breast cancer?

• Published in: Breast (Edinburgh) 2006-06, Vol.15 (3), p.355-362
• Main Authors: Lê, Monique G., Arriagada, Rodrigo, Bahi, Jacqueline, Pfeiffer, Frédérique, Cammoun, Mohamed, Tabbane, Françoise, Rubino, Carole
• Format: Article
• Language: English
• Subjects: Body Mass Index; Breast Feeding; Breast Neoplasms - epidemiology; Breast Neoplasms - pathology; Breast-feeding duration; Case only study; Educational Status; Female; Humans; Inflammation - epidemiology; Inflammatory breast cancer; Medicin och hälsovetenskap; Middle Aged; Multivariate Analysis; Odds Ratio; Reproductive risk factors; Risk Factors; Time Factors
• ISSN: 0960-9776; 1532-3080
• DOI: 10.1016/j.breast.2005.08.018

The aim of the study was to compare reproductive factors in patients with inflammatory breast cancer (IBC), and with non-inflammatory breast cancer (non-IBC). The study was performed in two centers: one French including 49 IBC patients and 140 non-IBC and another Tunisian including 97 IBC and 139 non-IBC. Unconditional logistic regression was used for the analyses. The French IBC patients had a lower educational level, a higher body mass index and a longer cumulative duration of breast-feeding, and they included a greater proportion of non-European women, than the non-IBC patients. In the multivariate analysis, only breast-feeding duration remained associated with the IBC status ( P = 1 0 - 3 ). These results could not be verified in the Tunisian series, because the duration of breast-feeding was unavailable in this center. This study suggests that the etiology of IBC might be different of that of non-IBC.