Left Ventricular Diastolic Dysfunction Late After Aortic Valve Replacement in Patients With Aortic Stenosis

Patients with severe aortic stenosis (AS) are known to have increased left ventricular (LV) mass and diastolic dysfunction. It has been suggested that LV mass and diastolic function normalize after aortic valve replacement (AVR). In the present study, change in LV mass index and diastolic function 1...

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Bibliographic Details
Published in:The American journal of cardiology 2005-09, Vol.96 (5), p.722-727
Main Authors: Gjertsson, Peter, Caidahl, Kenneth, Bech-Hanssen, Odd
Format: Article
Language:English
Subjects:
80 and over
Adult
Age Distribution
Aged
Aged, 80 and over
Aortic Valve Stenosis - surgery
Biological and medical sciences
Blood pressure
Cardiology
Cardiology. Vascular system
Coronary vessels
Doppler
Echocardiography
Echocardiography, Doppler
Endocardial and cardiac valvular diseases
Female
Follow-Up Studies
Heart
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Heart Valve Prosthesis Implantation - adverse effects
Humans
Left/etiology/physiopathology/ultrasonography
Left/physiology
Male
MEDICAL AND HEALTH SCIENCES
Medical sciences
MEDICIN OCH HÄLSOVETENSKAP
Middle Aged
Myocardial Contraction
Postoperative Complications
Retrospective Studies
Sex Distribution
Time Factors
Ventricular Dysfunction
Ventricular Dysfunction, Left - diagnostic imaging
Ventricular Dysfunction, Left - etiology
Ventricular Dysfunction, Left - physiopathology
Ventricular Function
Ventricular Function, Left - physiology
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Summary:Patients with severe aortic stenosis (AS) are known to have increased left ventricular (LV) mass and diastolic dysfunction. It has been suggested that LV mass and diastolic function normalize after aortic valve replacement (AVR). In the present study, change in LV mass index and diastolic function 10 years after AVR for AS was evaluated. Patients who underwent AVR from 1991 to 1993 (n = 57; mean age 67 ± 8.6 years at AVR, 58% men) were investigated with Doppler echocardiography preoperatively and 2 and 10 years postoperatively. Diastolic function was evaluated by integrating mitral and pulmonary venous flow data. Expected values for each patient, taking age into consideration, were defined using a control group (n = 71; age range 18 to 83 years). Patients were classified into 4 types: normal diastolic function (type A), mild diastolic dysfunction (type B), moderate diastolic dysfunction (type C), and severe diastolic dysfunction (type D). There was a reduction in LV mass index between the preoperative (161 ± 39 g/m 2) and 2-year follow-up (114 ± 28 g/m 2) examinations (p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2005.04.052