Myocardial velocities measured during adenosine, dobutamine and supine bicycle exercise: a tissue Doppler study in healthy volunteers

Summary Background:  Dobutamine stress echocardiography (DSE) quantified by tissue Doppler (TVI) have improved the diagnostic capacity of the procedure. Quantification of other stress modalities, e.g. adenosine stress echo (ASE) and exercise stress echocardiography (ESE) are necessary for assessing...

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Bibliographic Details
Published in:Clinical physiology and functional imaging 2004-09, Vol.24 (5), p.281-288
Main Authors: Saha, Samir K., Brodin, Lars-Åke, Lind, Britta, Svedenhag, Jan, Strååt, Eva, Gunnes, Sigurd
Format: Article
Language:English
Subjects:
Adenosine
Adult
Biological and medical sciences
coronary-artery-disease
diagnosis
diastolic function
Dobutamine
echocardiography
Echocardiography, Doppler - methods
Exercise Test - methods
Female
Fundamental and applied biological sciences. Psychology
Heart
Heart Ventricles - diagnostic imaging
Humans
hyperemia
Image Interpretation, Computer-Assisted - methods
ischemia
Male
Medicin och hälsovetenskap
Movement - physiology
Myocardial Contraction - physiology
non-pharmacological stress
pharmacological stress
quantitative stress echocardiography
regional systolic function
strain-rate
Stress, Mechanical
Supine Position - physiology
tissue Doppler
Ventricular Function
Ventricular Function, Left - physiology
Vertebrates: cardiovascular system
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Summary:Summary Background:  Dobutamine stress echocardiography (DSE) quantified by tissue Doppler (TVI) have improved the diagnostic capacity of the procedure. Quantification of other stress modalities, e.g. adenosine stress echo (ASE) and exercise stress echocardiography (ESE) are necessary for assessing any pathophysiological differences in different forms of stress. Methods:  Ten healthy individuals underwent ASE, DSE, and ESE during a span of 2–5 days. Left ventricular (LV) apical images at rest and peak stress (max) were postprocessed using TVI on a GE System FiVe equipment. ECG‐derived QRS duration (QRSD, ms), heart rate (HR, bpm), TVI‐estimated basal systolic velocities (S2V, cm s−1), ejection time (S2T, ms) and strain (S, %) were computed off‐line and compared. Longitudinal displacement imaging, tissue tracking, was also made. Results:  Data for ASE, DSE and ESE during peak stress were (HR: 84 ± 12***, 142 ± 19, 137 ± 27; P
ISSN:1475-0961
1475-097X
1475-097X
DOI:10.1111/j.1475-097X.2004.00563.x