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Early results of a single-blinded, randomized, controlled, Internet-based multicenter trial comparing Prolene and Vypro II mesh in Lichtenstein hernioplasty
The standard polypropylene mesh used in Lichtenstein's operation induces a strong foreign-tissue reaction with potentially harmful effects. A mesh with less polypropylene could possibly be beneficial. Six hundred men with inguinal hernias were randomized to Lichtenstein's operation with Pr...
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Published in: | Hernia : the journal of hernias and abdominal wall surgery 2004-05, Vol.8 (2), p.127-134 |
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container_title | Hernia : the journal of hernias and abdominal wall surgery |
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creator | Bringman, Sven Heikkinen, Timo-Jaakko Wollert, Staffan Osterberg, Johanna Smedberg, Sam Granlund, Håkan Ramel, Stig Felländer, Göran Anderberg, Bo |
description | The standard polypropylene mesh used in Lichtenstein's operation induces a strong foreign-tissue reaction with potentially harmful effects. A mesh with less polypropylene could possibly be beneficial.
Six hundred men with inguinal hernias were randomized to Lichtenstein's operation with Prolene or Vypro II in a single-blinded multicenter trial. The randomization was performed by a computer algorithm in a database through the Internet. All data were entered and directly validated in the database through the Internet.
The meshes had comparable results in return to work, return to daily activities, complications, postoperative pain, and quality of life during the first 8 weeks of rehabilitation.
Lichtenstein's operation with either Prolene or Vypro II is safe and well tolerated with an acceptable postoperative rehabilitation time and a high quality of life 2 months after surgery. The study was facilitated by the use of a database through the Internet. |
doi_str_mv | 10.1007/s10029-003-0192-3 |
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Six hundred men with inguinal hernias were randomized to Lichtenstein's operation with Prolene or Vypro II in a single-blinded multicenter trial. The randomization was performed by a computer algorithm in a database through the Internet. All data were entered and directly validated in the database through the Internet.
The meshes had comparable results in return to work, return to daily activities, complications, postoperative pain, and quality of life during the first 8 weeks of rehabilitation.
Lichtenstein's operation with either Prolene or Vypro II is safe and well tolerated with an acceptable postoperative rehabilitation time and a high quality of life 2 months after surgery. The study was facilitated by the use of a database through the Internet.</description><identifier>ISSN: 1265-4906</identifier><identifier>EISSN: 1248-9204</identifier><identifier>DOI: 10.1007/s10029-003-0192-3</identifier><identifier>PMID: 14648244</identifier><language>eng</language><publisher>France: Springer Nature B.V</publisher><subject>Adult ; Aged ; Hernia, Inguinal - surgery ; Humans ; Internet ; Male ; Middle Aged ; Polyglactin 910 ; Polypropylenes ; Postoperative Complications ; Quality of Life ; Randomized Controlled Trials as Topic - methods ; Single-Blind Method ; Surgical Mesh</subject><ispartof>Hernia : the journal of hernias and abdominal wall surgery, 2004-05, Vol.8 (2), p.127-134</ispartof><rights>Copyright Springer-Verlag 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2776-ffa6bd0a76321b0990bbc352e5f09d12cc463bc97e00d9a99ecee8b1ffea8b163</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14648244$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttp://kipublications.ki.se/Default.aspx?queryparsed=id:214648244$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Bringman, Sven</creatorcontrib><creatorcontrib>Heikkinen, Timo-Jaakko</creatorcontrib><creatorcontrib>Wollert, Staffan</creatorcontrib><creatorcontrib>Osterberg, Johanna</creatorcontrib><creatorcontrib>Smedberg, Sam</creatorcontrib><creatorcontrib>Granlund, Håkan</creatorcontrib><creatorcontrib>Ramel, Stig</creatorcontrib><creatorcontrib>Felländer, Göran</creatorcontrib><creatorcontrib>Anderberg, Bo</creatorcontrib><title>Early results of a single-blinded, randomized, controlled, Internet-based multicenter trial comparing Prolene and Vypro II mesh in Lichtenstein hernioplasty</title><title>Hernia : the journal of hernias and abdominal wall surgery</title><addtitle>Hernia</addtitle><description>The standard polypropylene mesh used in Lichtenstein's operation induces a strong foreign-tissue reaction with potentially harmful effects. A mesh with less polypropylene could possibly be beneficial.
Six hundred men with inguinal hernias were randomized to Lichtenstein's operation with Prolene or Vypro II in a single-blinded multicenter trial. The randomization was performed by a computer algorithm in a database through the Internet. All data were entered and directly validated in the database through the Internet.
The meshes had comparable results in return to work, return to daily activities, complications, postoperative pain, and quality of life during the first 8 weeks of rehabilitation.
Lichtenstein's operation with either Prolene or Vypro II is safe and well tolerated with an acceptable postoperative rehabilitation time and a high quality of life 2 months after surgery. 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A mesh with less polypropylene could possibly be beneficial.
Six hundred men with inguinal hernias were randomized to Lichtenstein's operation with Prolene or Vypro II in a single-blinded multicenter trial. The randomization was performed by a computer algorithm in a database through the Internet. All data were entered and directly validated in the database through the Internet.
The meshes had comparable results in return to work, return to daily activities, complications, postoperative pain, and quality of life during the first 8 weeks of rehabilitation.
Lichtenstein's operation with either Prolene or Vypro II is safe and well tolerated with an acceptable postoperative rehabilitation time and a high quality of life 2 months after surgery. The study was facilitated by the use of a database through the Internet.</abstract><cop>France</cop><pub>Springer Nature B.V</pub><pmid>14648244</pmid><doi>10.1007/s10029-003-0192-3</doi><tpages>8</tpages></addata></record> |
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subjects | Adult Aged Hernia, Inguinal - surgery Humans Internet Male Middle Aged Polyglactin 910 Polypropylenes Postoperative Complications Quality of Life Randomized Controlled Trials as Topic - methods Single-Blind Method Surgical Mesh |
title | Early results of a single-blinded, randomized, controlled, Internet-based multicenter trial comparing Prolene and Vypro II mesh in Lichtenstein hernioplasty |
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