Worsening of asthma in children allergic to cats, after indirect exposure to cat at school

Exposure to cat allergen at school might exacerbate symptoms in asthmatic children with cat allergy. To study this, we identified 410 children, 6-12 yr of age, who were being treated for asthma (inhaled steroids and beta-agonists), were allergic to cats, and had no cat at home. Peak expiratory flow...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2001-03, Vol.163 (3), p.694-698
Main Authors: ALMQVIST, Catarina, WICKMAN, Magnus, PERFETTI, Luca, BERGLIND, Niklas, RENSTRÖM, Anne, HEDREN, Marie, LARSSON, Kjell, HEDLIN, Gunilla, MALMBERG, Per
Format: Article
Language:English
Subjects:
Adolescent
Allergens - immunology
Animals
Asthma - immunology
Biological and medical sciences
Cats
Child
Chronic obstructive pulmonary disease, asthma
Female
Hair - immunology
Humans
Male
Medical sciences
Medicin och hälsovetenskap
Pneumology
Schools
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Summary:Exposure to cat allergen at school might exacerbate symptoms in asthmatic children with cat allergy. To study this, we identified 410 children, 6-12 yr of age, who were being treated for asthma (inhaled steroids and beta-agonists), were allergic to cats, and had no cat at home. Peak expiratory flow (PEF), asthma symptoms, medication, fever and/or sore throat, and contact with furred pets were recorded twice daily during the last week of summer holidays and the second and third weeks of school. The number of cat owners in each class was recorded. Ninety-two children with asthma reported no contact with furred pets. Among these, children who attended classes with > 18% (median value) cat owners reported significantly decreased PEF, more days with asthma symptoms, and increased use of medication after school started. Those in classes with < or = 18% cat owners reported no change. Children in classes with many cat owners ran a 9-fold increased risk of exacerbated asthma after school start compared with children in classes with few cat owners, after adjusting for age, sex, and fever and/or sore throat. Thus, asthma symptoms, PEF, and the use of asthma medication in children with cat allergy may be affected by indirect cat exposure at school.
ISSN:1073-449X
1535-4970
DOI:10.1164/ajrccm.163.3.2006114