Therapy with Cell Encapsulation for Substitution of Organ Function and Tumor Treatment

Cell encapsulation represents an innovative technique. However, clinical applications are sparse. Most experiments and clinical studies have been performed with either alginate or cellulose sulfate capsules, containing several cell lines and a broad variety of applications, ranging all the way from...

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Bibliographic Details
Published in:Advanced engineering materials 2009-08, Vol.11 (8), p.B129-B135
Main Authors: Löhr, J. Matthias, Heuchel, Rainer, Jesnowski, Ralf, Wallrapp, Christine
Format: Article
Language:English
Subjects:
Biological and medical sciences
cell encapsulation
cell therapy
gene therapy
Medical sciences
Medicin och hälsovetenskap
Other treatments
stem cell
Treatment. General aspects
Tumors
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Description
Summary:Cell encapsulation represents an innovative technique. However, clinical applications are sparse. Most experiments and clinical studies have been performed with either alginate or cellulose sulfate capsules, containing several cell lines and a broad variety of applications, ranging all the way from substitution for impaired organ function and release of cytokines or growth factors to gene‐directed enzyme prodrug therapy. A few clinical studies have been conducted and/or are under way.
ISSN:1438-1656
1527-2648
DOI:10.1002/adem.200800409