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How interactions between ADHD and schools affect educational achievement: a family‐based genetically sensitive study

Background Children with ADHD tend to achieve less than their peers in school. It is unknown whether schools moderate this association. Nonrandom selection of children into schools related to variations in their ADHD risk poses a methodological problem. Methods We linked data on ADHD symptoms of ina...

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Published in:Journal of child psychology and psychiatry 2022-10, Vol.63 (10), p.1174-1185
Main Authors: Cheesman, Rosa, Eilertsen, Espen M., Ayorech, Ziada, Borgen, Nicolai T., Andreassen, Ole A., Larsson, Henrik, Zachrisson, Henrik, Torvik, Fartein A., Ystrom, Eivind
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container_issue 10
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container_title Journal of child psychology and psychiatry
container_volume 63
creator Cheesman, Rosa
Eilertsen, Espen M.
Ayorech, Ziada
Borgen, Nicolai T.
Andreassen, Ole A.
Larsson, Henrik
Zachrisson, Henrik
Torvik, Fartein A.
Ystrom, Eivind
description Background Children with ADHD tend to achieve less than their peers in school. It is unknown whether schools moderate this association. Nonrandom selection of children into schools related to variations in their ADHD risk poses a methodological problem. Methods We linked data on ADHD symptoms of inattention and hyperactivity and parent–child ADHD polygenic scores (PGS) from the Norwegian Mother, Father, and Child Cohort Study (MoBa) to achievement in standardised tests and school identifiers. We estimated interactions of schools with individual differences between students in inattention, hyperactivity, and ADHD‐PGS using multilevel models with random slopes for ADHD effects on achievement over schools. In our PGS analyses, we adjust for parental selection of schools by adjusting for parental ADHD‐PGS (a within‐family PGS design). We then tested whether five school sociodemographic measures explained any interactions. Results Analysis of up to 23,598 students attending 2,579 schools revealed interactions between school and ADHD effects on achievement. The variability between schools in the effects of inattention, hyperactivity and within‐family ADHD‐PGS on achievement was 0.08, 0.07 and 0.05 SDs, respectively. For example, the average effect of inattention on achievement was β = −0.23 (SE = 0.009), but in 2.5% of schools with the weakest effects, the value was −0.07 or less. ADHD has a weaker effect on achievement in higher‐performing schools. Schools make more of a difference to the achievements of students with higher levels of ADHD, explaining over four times as much variance in achievement for those with high versus average inattention symptoms. School sociodemographic measures could not explain the ADHD‐by‐school interactions. Conclusions Although ADHD symptoms and genetic risk tend to hinder achievement, schools where their effects are weaker do exist. Differences between schools in support for children with ADHD should be evened out.
doi_str_mv 10.1111/jcpp.13656
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It is unknown whether schools moderate this association. Nonrandom selection of children into schools related to variations in their ADHD risk poses a methodological problem. Methods We linked data on ADHD symptoms of inattention and hyperactivity and parent–child ADHD polygenic scores (PGS) from the Norwegian Mother, Father, and Child Cohort Study (MoBa) to achievement in standardised tests and school identifiers. We estimated interactions of schools with individual differences between students in inattention, hyperactivity, and ADHD‐PGS using multilevel models with random slopes for ADHD effects on achievement over schools. In our PGS analyses, we adjust for parental selection of schools by adjusting for parental ADHD‐PGS (a within‐family PGS design). We then tested whether five school sociodemographic measures explained any interactions. Results Analysis of up to 23,598 students attending 2,579 schools revealed interactions between school and ADHD effects on achievement. The variability between schools in the effects of inattention, hyperactivity and within‐family ADHD‐PGS on achievement was 0.08, 0.07 and 0.05 SDs, respectively. For example, the average effect of inattention on achievement was β = −0.23 (SE = 0.009), but in 2.5% of schools with the weakest effects, the value was −0.07 or less. ADHD has a weaker effect on achievement in higher‐performing schools. Schools make more of a difference to the achievements of students with higher levels of ADHD, explaining over four times as much variance in achievement for those with high versus average inattention symptoms. School sociodemographic measures could not explain the ADHD‐by‐school interactions. Conclusions Although ADHD symptoms and genetic risk tend to hinder achievement, schools where their effects are weaker do exist. Differences between schools in support for children with ADHD should be evened out.</description><identifier>ISSN: 0021-9630</identifier><identifier>ISSN: 1469-7610</identifier><identifier>EISSN: 1469-7610</identifier><identifier>DOI: 10.1111/jcpp.13656</identifier><identifier>PMID: 35789088</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Academic achievement ; Academic Success ; ADHD ; Attention Deficit Disorder with Hyperactivity - diagnosis ; Attention Deficit Disorder with Hyperactivity - epidemiology ; Attention Deficit Disorder with Hyperactivity - genetics ; Attention deficit hyperactivity disorder ; Averages ; Children ; Cohort analysis ; Cohort Studies ; Educational Status ; Family (Sociological Unit) ; gene-environment interaction ; Genetic susceptibility ; genetics ; Humans ; Hyperactivity ; Individual differences ; Medicin och hälsovetenskap ; Methodological problems ; Parents &amp; parenting ; school ; school performance ; Schools ; Sociodemographics ; Students</subject><ispartof>Journal of child psychology and psychiatry, 2022-10, Vol.63 (10), p.1174-1185</ispartof><rights>2022 The Authors. published by John Wiley &amp; Sons Ltd on behalf of Association for Child and Adolescent Mental Health.</rights><rights>2022 The Authors. 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It is unknown whether schools moderate this association. Nonrandom selection of children into schools related to variations in their ADHD risk poses a methodological problem. Methods We linked data on ADHD symptoms of inattention and hyperactivity and parent–child ADHD polygenic scores (PGS) from the Norwegian Mother, Father, and Child Cohort Study (MoBa) to achievement in standardised tests and school identifiers. We estimated interactions of schools with individual differences between students in inattention, hyperactivity, and ADHD‐PGS using multilevel models with random slopes for ADHD effects on achievement over schools. In our PGS analyses, we adjust for parental selection of schools by adjusting for parental ADHD‐PGS (a within‐family PGS design). We then tested whether five school sociodemographic measures explained any interactions. Results Analysis of up to 23,598 students attending 2,579 schools revealed interactions between school and ADHD effects on achievement. The variability between schools in the effects of inattention, hyperactivity and within‐family ADHD‐PGS on achievement was 0.08, 0.07 and 0.05 SDs, respectively. For example, the average effect of inattention on achievement was β = −0.23 (SE = 0.009), but in 2.5% of schools with the weakest effects, the value was −0.07 or less. ADHD has a weaker effect on achievement in higher‐performing schools. Schools make more of a difference to the achievements of students with higher levels of ADHD, explaining over four times as much variance in achievement for those with high versus average inattention symptoms. School sociodemographic measures could not explain the ADHD‐by‐school interactions. Conclusions Although ADHD symptoms and genetic risk tend to hinder achievement, schools where their effects are weaker do exist. 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It is unknown whether schools moderate this association. Nonrandom selection of children into schools related to variations in their ADHD risk poses a methodological problem. Methods We linked data on ADHD symptoms of inattention and hyperactivity and parent–child ADHD polygenic scores (PGS) from the Norwegian Mother, Father, and Child Cohort Study (MoBa) to achievement in standardised tests and school identifiers. We estimated interactions of schools with individual differences between students in inattention, hyperactivity, and ADHD‐PGS using multilevel models with random slopes for ADHD effects on achievement over schools. In our PGS analyses, we adjust for parental selection of schools by adjusting for parental ADHD‐PGS (a within‐family PGS design). We then tested whether five school sociodemographic measures explained any interactions. Results Analysis of up to 23,598 students attending 2,579 schools revealed interactions between school and ADHD effects on achievement. The variability between schools in the effects of inattention, hyperactivity and within‐family ADHD‐PGS on achievement was 0.08, 0.07 and 0.05 SDs, respectively. For example, the average effect of inattention on achievement was β = −0.23 (SE = 0.009), but in 2.5% of schools with the weakest effects, the value was −0.07 or less. ADHD has a weaker effect on achievement in higher‐performing schools. Schools make more of a difference to the achievements of students with higher levels of ADHD, explaining over four times as much variance in achievement for those with high versus average inattention symptoms. School sociodemographic measures could not explain the ADHD‐by‐school interactions. Conclusions Although ADHD symptoms and genetic risk tend to hinder achievement, schools where their effects are weaker do exist. 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subjects Academic achievement
Academic Success
ADHD
Attention Deficit Disorder with Hyperactivity - diagnosis
Attention Deficit Disorder with Hyperactivity - epidemiology
Attention Deficit Disorder with Hyperactivity - genetics
Attention deficit hyperactivity disorder
Averages
Children
Cohort analysis
Cohort Studies
Educational Status
Family (Sociological Unit)
gene-environment interaction
Genetic susceptibility
genetics
Humans
Hyperactivity
Individual differences
Medicin och hälsovetenskap
Methodological problems
Parents & parenting
school
school performance
Schools
Sociodemographics
Students
title How interactions between ADHD and schools affect educational achievement: a family‐based genetically sensitive study
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