Long-term secondary prevention and outcome following acute coronary syndrome: Real-world results from the Swedish Primary Care Cardiovascular Database (SPCCD)

• Published in: European journal of preventive cardiology 2024-05, Vol.31 (7), p.812-821
• Main Authors: Bentzel, Sara, Ljungman, Charlotta, Hjerpe, Per, Schiöler, Linus, Manhem, Karin, Bengtsson Boström, Kristina, Kahan, Thomas, Mourtzinis, Georgios
• Format: Article
• Language: English
• Subjects: Cardiac and Cardiovascular Systems; Kardiologi; Medicin och hälsovetenskap
• ISSN: 2047-4873; 2047-4881; 2047-4881
• DOI: 10.1093/eurjpc/zwad389

Most studies of treatment adherence after acute coronary syndrome (ACS) are based on prescribed drugs and lack long-term follow-up or consecutive data on risk factor control. We studied the long-term treatment adherence, risk factor control and its association to recurrent ACS and death. We retrospectively included 3765 patients (mean age 75 years, 40% women) with incident ACS from 1 January 2006 until 31 December 2010 from the SPCCD-SKA database. All patients were followed until 31 December 2014 or death. We recorded blood pressure (BP), low density lipoprotein-cholesterol (LDL-C), recurrent ACS and death. We used data on dispensed drugs to calculate proportion of days covered for secondary prevention medications. Cox regressions were used to analyse the association of achieved BP and LDL-C to recurrent ACS and death. The median follow-up time was 4.8 years. Proportion of patients that reached BP