Current methods of analysis for the determination of trichothecene mycotoxins in food

This article describes the trends in analytical techniques for the determination of trichothecene mycotoxins, namely deoxynivalenol, and T-2 and HT-2 toxins in cereals and cereal products with particular emphasis on screening and rapid approaches. The driving force behind the changing methodologies...

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Bibliographic Details
Published in:TrAC, Trends in analytical chemistry (Regular ed.) Trends in analytical chemistry (Regular ed.), 2011-02, Vol.30 (2), p.192-203
Main Authors: Meneely, Julie P., Ricci, Francesco, van Egmond, Hans P., Elliott, Christopher T.
Format: Article
Language:English
Subjects:
aflatoxin b-1
b trichothecenes
Deoxynivalenol (DON)
differential-pulse polarography
Electrochemical biosensor
electrochemical immunosensor
Food analysis
HT-2 toxin
immunoassay
Liquid chromatography
Mass spectrometry
monoclonal-antibodies
Optical biosensor
performance liquid-chromatography
Screening assay
T-2 toxin
tandem mass-spectrometry
Trichothecene mycotoxin
wheat
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Summary:This article describes the trends in analytical techniques for the determination of trichothecene mycotoxins, namely deoxynivalenol, and T-2 and HT-2 toxins in cereals and cereal products with particular emphasis on screening and rapid approaches. The driving force behind the changing methodologies is mainly attributed to legislative demands. However, for commercial and governmental testing laboratories, the need to use validated official methods is ever increasing to ensure quality assurance of results. Much research has been undertaken to improve screening assays, highlighted by the number of new methods using a variety of formats and platforms, including optical and electrochemical biosensors. Significant advances in the traditional reference methods have also been demonstrated in addition to the emergence of a variety of commercial immunoaffinity and solid-phase extraction columns for clean up. The use of liquid chromatography coupled to tandem mass spectrometry for mycotoxin detection is ever increasing, allowing simultaneous determination of many toxins in various sample matrices.
ISSN:0165-9936
1879-3142
DOI:10.1016/j.trac.2010.06.012