Associations of alpha-linolenic acid and linoleic acid with risk factors for coronary heart disease

Prevention of coronary heart disease (CHD) in high-risk subjects. To investigate the associations of dietary intake of alpha-linolenic acid (ALA) and linoleic acid (LA) as assessed by food frequency questionnaire and in the plasma cholesteryl ester (CE), with CHD risk factors. Baseline data of a dou...

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Bibliographic Details
Published in:European journal of clinical nutrition 2000-12, Vol.54 (12), p.865-871
Main Authors: BEMELMANS, W. J. E, MUSKIET, F. A. J, FESKENS, E. J. M, DE VRIES, J. H. M, BROER, J, MAY, J. F, MEYBOOM-DE JONG, B
Format: Article
Language:English
Subjects:
Acids
Adult
Afdeling Humane voeding
Aged
alpha-Linolenic Acid - blood
alpha-Linolenic Acid - pharmacology
Biological and medical sciences
Blindness
Blood pressure
Blood Pressure - drug effects
Cardiovascular disease
Cardiovascular diseases
Cholesterol
Cholesterol Esters - blood
Cholesterol Esters - chemistry
Clinical nutrition
Clinical trials
Coronary artery disease
Coronary Disease - diet therapy
Coronary Disease - etiology
Coronary Disease - prevention & control
Coronary heart disease
Cross-Sectional Studies
Design factors
Diet
Dietary Fats - pharmacology
Dietary intake
Diseases of the cardiovascular system
Double-Blind Method
Energy
Female
Food intake
Health aspects
Heart diseases
Human Nutrition
Human Nutrition & Health
Human Nutrition (HNE)
Humane Voeding
Humane Voeding & Gezondheid
Humans
Hypercholesterolemia
Hypercholesterolemia - complications
Linoleic acid
Linoleic Acid - adverse effects
Linoleic Acid - blood
Linoleic acids
Linolenic acid
Linolenic acids
Male
Margarine
Medical sciences
Middle Aged
Multivariate analysis
Nutrition
Prevention
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Risk analysis
Risk Factors
Surveys and Questionnaires
Triglycerides
Triglycerides - analysis
VLAG
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Summary:Prevention of coronary heart disease (CHD) in high-risk subjects. To investigate the associations of dietary intake of alpha-linolenic acid (ALA) and linoleic acid (LA) as assessed by food frequency questionnaire and in the plasma cholesteryl ester (CE), with CHD risk factors. Baseline data of a double-blind, randomized placebo-controlled trial. Subjects have hypercholesterolemia (6.0-8.0 mmol/l) and at least two other CHD risk factors (n=266). The reported dietary ALA and LA intakes and the LA/ALA ratio were associated with the contents in the CE (r=0.37, r=0.21, and r=0.42, respectively; P
ISSN:0954-3007
1476-5640
DOI:10.1038/sj.ejcn.1601102