Enzymatic Promiscuity： ＂Amano＂ Lipase AS-catalysed Synthesis of Naphthopyran Derivatives in Anhydrous Media

＂Amano＂ lipase AS（lipase from Aspergillus niger）, which naturally hydrolyzes triglycerides, was found promiscuously to catalyze multi-component reactions of aromatic aldehydes with malononitrile and β-naphthol to prepare naphthopyran derivatives in anhydrous organic solvents in moderate to good yiel...

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Bibliographic Details
Published in:Chemical research in Chinese universities 2014-06, Vol.30 (3), p.396-399
Main Authors: Jiang, Ling, Yu, Hongwei
Format: Article
Language:English
Subjects:
Analytical Chemistry
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Inorganic Chemistry
Organic Chemistry
Physical Chemistry
催化
合成
吡喃衍生物
多组分反应
水介质
脂肪酶
萘衍生物
酶法
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Summary:＂Amano＂ lipase AS（lipase from Aspergillus niger）, which naturally hydrolyzes triglycerides, was found promiscuously to catalyze multi-component reactions of aromatic aldehydes with malononitrile and β-naphthol to prepare naphthopyran derivatives in anhydrous organic solvents in moderate to good yields.
ISSN:1005-9040
2210-3171
DOI:10.1007/s40242-014-3442-2