Modulation by Biogenic Amines for the Hemocyte Count and Prophenoloxidase Exocytosis via Receptors in Litopenaeus vannamei

Hemocyte counts and phenoloxidase（PO）activity were examined after hemolymph being incubated in dopamine（DA）,noradrenaline（NE）and serotonin（5-HT）.Results showed that all the three biogenic amines（BAs）had a significant impact on total hemocyte count（THC）,differential hemocyte count（DHC）,and intracellu...

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Bibliographic Details
Published in:Journal of Ocean University of China 2011-12, Vol.10 (4), p.425-432
Main Authors: Pan, Luqing, Liu, Huijie, Yu, Jinhong
Format: Article
Language:English
Subjects:
Amines
Crustaceans
Dopamine
Earth and Environmental Science
Earth Sciences
Immune system
Litopenaeus vannamei
Marine
Marine biology
Meteorology
Oceanography
Serotonin
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Summary:Hemocyte counts and phenoloxidase（PO）activity were examined after hemolymph being incubated in dopamine（DA）,noradrenaline（NE）and serotonin（5-HT）.Results showed that all the three biogenic amines（BAs）had a significant impact on total hemocyte count（THC）,differential hemocyte count（DHC）,and intracelluar and extracelluar phenoloxidase（PO）activity.Among these Bas,DA had the strongest effect on the above parameters,whereas 5-HT had the least effect.Preincubation with D1 receptor antagonist SCH23390,D2 receptor antagonist Sulpiride and 1：1 admixture of the two could significantly inhibit the effect of DA on these parameters.SCH23390 showed a stronger inhibitory effect than Sulpiride,and the admixture exhibited the strongest effect.These results suggested that the change of hemocyte count and activation of prophenoloxidase（proPO）system in Litopenaeusvan-namei hemocyte can be regulated by BAs,and DA modulates the two parameters via its receptors.
ISSN:1672-5182
1993-5021
1672-5174
DOI:10.1007/s11802-011-1811-8