Handmade tri-leaflet ePTFE conduits versus homografts for right ventricular outflow tract reconstruction

• Published in: World journal of pediatrics : WJP 2022-03, Vol.18 (3), p.206-213
• Main Authors: Wang, Guan-Xi, Mao, Feng-Qun, Ma, Kai, Liu, Rui, Pang, Kun-Jing, Zhang, Sen, Yang, Yang, Zhang, Ben-Qing, Li, Shou-Jun
• Format: Article
• Language: English
• Subjects: Critical Care Medicine; Imaging; Intensive; Maternal and Child Health; Medicine; Medicine & Public Health; Original Article; Pediatric Surgery; Pediatrics; Radiology; Surgery
• ISSN: 1708-8569; 1867-0687
• DOI: 10.1007/s12519-021-00498-x

Background This study aimed to investigate the performance of handmade tri-leaflet expanded polytetrafluoroethylene (ePTFE) conduits in the absence of a suitable homograft. Methods Patients who underwent right ventricular outflow tract reconstruction with tri-leaflet ePTFE conduits or homografts between December 2016 and August 2020 were included. The primary endpoint was the incidence of moderate or severe conduit stenosis (≥ 36 mmHg) and/or moderate or severe insufficiency. The secondary endpoint was the incidence of severe conduit stenosis (≥ 64 mmHg) and/or severe insufficiency. Results There were 102 patients in the ePTFE group and 52 patients in the homograft group. The median age was younger [34.5 (interquartile range: 20.8–62.8) vs. 60.0 (interquartile range: 39.3–81.0) months, P  = 0.001] and the median weight was lower [13.5 (10.0–19.0) vs. 17.8 (13.6–25.8) kg, P  = 0.003] in the ePTFE group. The conduit size was smaller (17.9 ± 2.2 vs. 20.5 ± 3.0 mm, P